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TRAF1 and SCNM1
Data Source:
BioGRID
(two hybrid, two hybrid)
TRAF1
SCNM1
Description
TNF receptor associated factor 1
sodium channel modifier 1
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Cytoplasmic Side Of Plasma Membrane
Plasma Membrane Signaling Receptor Complex
Nucleus
Nuclear Speck
Molecular Function
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
Identical Protein Binding
Protein Binding
Enzyme Binding
Metal Ion Binding
Biological Process
Apoptotic Process
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Tumor Necrosis Factor-mediated Signaling Pathway
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of JNK Cascade
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein-containing Complex Assembly
Protein K63-linked Ubiquitination
Regulation Of Extrinsic Apoptotic Signaling Pathway
Alternative MRNA Splicing, Via Spliceosome
RNA Splicing
Pathways
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
Drugs
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Asthma (
32296059
)
Celiac disease or Rheumatoid arthritis (
21383967
)
Eosinophil percentage of white cells (
32888494
)
Lymphocyte counts (
32888494
27863252
)
Lymphocyte percentage of white cells (
32888494
)
Monocyte count (
32888494
)
Pulse pressure (
30578418
)
Refractive error (
32231278
)
Rheumatoid arthritis (
30891314
24782177
23143596
24390342
20453842
19503088
)
Rheumatoid arthritis (ACPA-positive) (
23143596
24532676
)
White blood cell count (
32888494
)
Interacting Genes
245 interacting genes:
A1CF
ABHD17A
ACTN3
AKAP17A
AQP1
ARID5A
ARNT2
ARSJ
BARD1
BCAS2
BCL6
BEX2
BEX3
BIRC2
BIRC3
C1orf109
C1orf216
C2CD6
C4orf45
CARHSP1
CASP10
CASP3
CASP6
CASP8
CCDC116
CCDC120
CCDC146
CCDC185
CCDC187
CCDC198
CCHCR1
CD40
CDCA3
CDK18
CDKN1A
CDKN2B
CFLAR
CHCHD3
COX5B
CRACR2A
CRY2
CRYGA
CYB5R2
DEPTOR
DGCR6
DMRT3
DOK3
DUSP13
DUSP21
DUSP4
EBF2
EDAR
EHHADH
ENKD1
EWSR1
FAM161A
FAM161B
FAM86C1P
FBF1
FBXL18
FOSL2
GADD45GIP1
GATA1
GATA2
GATAD2B
GCA
GCM2
GEM
GFI1B
GIT2
GLIS3
GLRX3
GMCL2
GNG5
GOLGA2
GORASP2
GRAP2
HAUS1
HELT
HEY2
HGS
HIVEP3
HMG20B
HNRNPM
HOXA1
HOXB5
HOXC8
HOXD12
IKBKB
JOSD1
KANK2
KIAA1217
KIF1A
KLHL38
KPNA2
KRT3
KRT75
LATS1
LCOR
LIN37
LMNTD2
LNX1
LNX2
LRRN1
LTBR
MACIR
MAP3K14
MAP6
MAPRE2
MATR3
METTL17
MORN3
MOS
MSGN1
MYEF2
MYOZ1
NEBL
NOL4L-DT
NTAQ1
NUFIP2
NUP58
OLIG3
PATZ1
PBX3
PDE4D
PHF21A
PIN1
PITX1
PITX2
PKN1
PLAC8
PLEKHN1
POM121L4P
POP5
PPP1R13B
PPP1R32
PRDM7
PRKAB2
PSMA1
PSMB1
QRICH1
RASAL2
RASSF5
RBCK1
RBM41
RBM45
RCOR3
RIIAD1
RIPK1
RIPK2
RIPOR3
RIPPLY1
RNF31
RTP5
SAMD11
SCNM1
SDCBP2
SH3GLB2
SHARPIN
SHC3
SHFL
SIK3
SLC25A48
SLC25A6
SNRNP25
SNW1
SOHLH1
SPATA46
SPG21
SPOP
SRC
SSC5D
STK3
SUMO2
SYCE1
TANK
TBC1D16
TBC1D8
TBX18
TCEA2
TCF7L2
TCL1A
TEAD4
TFAP2D
TFAP4
TFPT
THAP7
TICAM1
TIFA
TLE5
TNFAIP3
TNFRSF11A
TNFRSF12A
TNFRSF14
TNFRSF17
TNFRSF18
TNFRSF19
TNFRSF1A
TNFRSF1B
TNFRSF4
TNFRSF8
TNFRSF9
TNFSF9
TRADD
TRAF2
TRAF3IP2
TRAF6
TRAIP
TRIM23
TRIM37
TRIM42
TRPV6
TSHZ2
TSSC4
USP2
USP7
UTP14C
VEZF1
WAC
ZBTB1
ZBTB16
ZC2HC1C
ZFYVE21
ZFYVE26
ZIC1
ZNF124
ZNF20
ZNF23
ZNF250
ZNF417
ZNF440
ZNF490
ZNF502
ZNF512B
ZNF564
ZNF572
ZNF581
ZNF587
ZNF627
ZNF648
ZNF662
ZNF669
ZNF688
ZNF697
ZNF844
177 interacting genes:
ADAMTSL4
AKAP9
AVPI1
AXIN2
BACH2
BEND7
BHLHB9
BLZF1
CALCOCO2
CARD10
CARD9
CBY2
CCDC136
CCDC28B
CCDC33
CCDC74B
CCDC85B
CDR2
CDR2L
CEP44
CEP70
CEP76
CHIC2
CIB3
COG6
CTDSP1
CYSRT1
CYTIP
DVL2
EZHIP
FAM161A
FAM228A
FANCL
FHL2
FHL5
FNDC11
FRS3
FSD2
GAS8
GIGYF1
GOLGA2
GOLGA6L9
HAP1
HMBOX1
HMG20A
HOMER3
HOMEZ
HOOK2
HSF2BP
IKZF1
IKZF3
INCA1
IRAK1BP1
JAKMIP1
KANK2
KATNBL1
KIFC3
KLF15
KRT27
KRT31
KRT33B
KRT34
KRT35
KRT38
KRT39
KRT75
KRTAP1-1
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP5-9
LCN2
LDOC1
LHX1
LHX3
LIMS1
LNX1
LNX2
LRP2BP
LZTS1
LZTS2
MCM6
MDFI
MEOX2
MID2
MIPOL1
MKRN3
MORN3
MRPL28
MSS51
MTUS2
MYLIP
MYO1F
NAB2
NAP1L2
NBPF19
NDUFB7
NFKBID
NOTCH2NLA
NUTM1
PBX4
PDE4DIP
PDLIM7
PFDN5
PIBF1
PICK1
PIH1D1
PLSCR1
PNMA1
PNMA2
PPP1R16A
PPP1R16B
PRDM14
PRNP
PRR5L
PSTPIP1
RBAK
RBM11
RBM48
RDM1
REL
RHOH
RINT1
RORB
RPGRIP1
RPH3AL
SMARCD1
SORBS3
SSX2IP
STX11
STX19
SYCE1
TAX1BP1
TFIP11
TLE5
TNNI1
TP53BP2
TRAF1
TRAF2
TRIB3
TRIM10
TRIM23
TRIM27
TRIM37
TRIM42
TRIM54
TTC23L
UBXN11
USH1G
USHBP1
VIM
VMAC
VPS52
VWC2
ZBTB1
ZBTB14
ZDHHC17
ZGPAT
ZIM2
ZMAT1
ZMYND12
ZNF135
ZNF19
ZNF20
ZNF202
ZNF438
ZNF511
ZNF526
ZNF547
ZNF552
ZNF641
ZNF688
ZNF76
ZNF774
ZNF829
Entrez ID
7185
79005
HPRD ID
03418
12162
Ensembl ID
ENSG00000056558
ENSG00000163156
Uniprot IDs
Q13077
Q9BWG6
PDB IDs
3M0D
5E1T
5H10
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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