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UBE2D4 and DTX3L
Data Source:
BioGRID
(two hybrid)
UBE2D4
DTX3L
Description
ubiquitin conjugating enzyme E2 D4 (putative)
deltex E3 ubiquitin ligase 3L
Image
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleus
Nucleoplasm
Cytoplasm
Lysosome
Lysosomal Membrane
Early Endosome
Cytosol
Early Endosome Membrane
Protein-containing Complex
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Conjugating Enzyme Activity
Ubiquitin-protein Transferase Activity
Enzyme Inhibitor Activity
Protein Binding
Enzyme Activator Activity
Enzyme Binding
Histone Binding
Ubiquitin-like Protein Ligase Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
STAT Family Protein Binding
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Protein Polyubiquitination
Positive Regulation Of Defense Response To Virus By Host
Double-strand Break Repair
Ubiquitin-dependent Protein Catabolic Process
Cellular Response To DNA Damage Stimulus
Notch Signaling Pathway
Endosome To Lysosome Transport
Histone Monoubiquitination
Protein Transport
Viral Process
Protein Ubiquitination
Positive Regulation Of Protein Binding
Histone H2A Ubiquitination
Histone H2B Ubiquitination
Positive Regulation Of Chromatin Binding
Innate Immune Response
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Ubiquitin-protein Transferase Activity
Defense Response To Virus
Protein Autoubiquitination
Protein K48-linked Ubiquitination
Positive Regulation Of Protein Localization To Nucleus
Positive Regulation Of NAD+ ADP-ribosyltransferase Activity
Positive Regulation Of Protein Localization To Early Endosome
Positive Regulation Of Receptor Catabolic Process
Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Low density lipoprotein cholesterol levels (
32154731
)
Major depressive disorder (
22472876
)
Interacting Genes
109 interacting genes:
AMFR
ARIH2
BFAR
BIRC8
CADPS2
CHFR
CNOT4
DAZAP2
DTX1
DTX2
DTX3
DTX3L
DZIP3
H3C1
H4C1
IKBKG
INCA1
ITCH
LNX1
LRSAM1
MAGEA11
MAP3K1
MARCHF3
MDM2
MGRN1
MIB1
MID1
MID2
MKRN1
MKRN2
MKRN3
MUL1
MYBL2
MYLIP
OTUB1
PHF7
PJA2
POLR2E
PRKN
RBCK1
RCHY1
REL
RFWD3
RING1
RLIM
RMND5B
RNF10
RNF103
RNF11
RNF111
RNF114
RNF115
RNF125
RNF126
RNF13
RNF130
RNF138
RNF14
RNF150
RNF165
RNF166
RNF167
RNF181
RNF185
RNF2
RNF216
RNF26
RNF31
RNF38
RNF4
RNF43
RNF5
RNF7
SIAH1
STUB1
TOPORS
TRAF6
TRAF7
TRIM10
TRIM17
TRIM2
TRIM23
TRIM25
TRIM27
TRIM3
TRIM31
TRIM35
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM54
TRIM62
TRIM8
UBA1
UBC
UBE4A
UBOX5
UBTD1
UBTD2
UFM1
UHRF2
UVSSA
XIAP
ZNRF1
ZNRF2
ZNRF4
20 interacting genes:
DTX1
H2AZ2
ITCH
PARP9
PHF7
RNF111
SPG21
TRIM9
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2I
UBE2K
UBE2R2
UBE2W
Entrez ID
51619
151636
HPRD ID
14242
16843
Ensembl ID
ENSG00000078967
ENSG00000163840
Uniprot IDs
A0A024RA90
Q9UQL0
Q9Y2X8
Q8TDB6
PDB IDs
3PG6
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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