TMED9 and DDX54

Data Source:
BioGRID (two hybrid)

		TMED9	DDX54
Description		transmembrane p24 trafficking protein 9	DEAD-box helicase 54
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Synaptic Vesicle Integral Component Of Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle Trans-Golgi Network Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Golgi Apparatus Membrane
	Molecular Function	Protein Binding Syntaxin Binding	Transcription Corepressor Activity RNA Binding RNA Helicase Activity Signaling Receptor Binding ATP Binding Estrogen Receptor Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Positive Regulation Of Organelle Organization Protein Exit From Endoplasmic Reticulum Early Endosome To Golgi Transport COPI Coating Of Golgi Vesicle	RRNA Processing RNA Processing RNA Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Transcription, DNA-templated
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Body mass index ( 26426971) Response to fenofibrate (adiponectin levels) ( 23149075)
Interacting Genes		13 interacting genes: AQP9 CDC42 CKMT2 COPZ1 DDX54 ITM2A MTF2 NMT2 PLPPR2 SEC22A SEC23B THAP8 TMEM60	19 interacting genes: APP CASK CSNK2A1 DVL3 DYNLT1 ESR1 ESR2 NEDD4 NEDD4L NR3C1 PGR PJA1 POLR2G PTPRD SEMA4A SMURF1 TMED9 YWHAE ZNF394
Entrez ID		54732	79039
HPRD ID		09975	13129
Ensembl ID		ENSG00000184840	ENSG00000123064
Uniprot IDs		A0A024R7M0 Q9BVK6	Q8TDD1
PDB IDs
Enriched GO Terms of Interacting Partners?
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