TMED9 and NMT2

Data Source:
BioGRID (two hybrid)

		TMED9	NMT2
Description		transmembrane p24 trafficking protein 9	N-myristoyltransferase 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Synaptic Vesicle Integral Component Of Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle Trans-Golgi Network Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Exosome	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Extrinsic Component Of Membrane Host Cell
	Molecular Function	Protein Binding Syntaxin Binding	Glycylpeptide N-tetradecanoyltransferase Activity Protein Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Positive Regulation Of Organelle Organization Protein Exit From Endoplasmic Reticulum Early Endosome To Golgi Transport COPI Coating Of Golgi Vesicle	N-terminal Peptidyl-glycine N-myristoylation Regulation Of Rhodopsin Mediated Signaling Pathway Intracellular Transport Of Virus
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Membrane binding and targetting of GAG proteins Inactivation, recovery and regulation of the phototransduction cascade
Drugs			Myristoyl-Coa S-(2-oxo)pentadecylcoa 1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL (Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE
Diseases
GWAS		Obesity-related traits ( 23251661) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Clozapine-induced agranulocytosis ( 25187353) Mild to moderate chronic kidney disease ( 31178898) Osteoporosis-related phenotypes (MTAG) ( 32107650) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		13 interacting genes: AQP9 CDC42 CKMT2 COPZ1 DDX54 ITM2A MTF2 NMT2 PLPPR2 SEC22A SEC23B THAP8 TMEM60	14 interacting genes: ACBD6 ANXA4 ANXA7 APP BCL2 BTF3 CASP3 CSNK2B PPP1CC PRKCZ SMN1 TK1 TMED9 TP53
Entrez ID		54732	9397
HPRD ID		09975	11948
Ensembl ID		ENSG00000184840	ENSG00000152465
Uniprot IDs		A0A024R7M0 Q9BVK6	B3KT39 O60551 Q5VUC6
PDB IDs			4C2X 6PAU
Enriched GO Terms of Interacting Partners?
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