TMED9 and MTF2

Data Source:
BioGRID (two hybrid)

		TMED9	MTF2
Description		transmembrane p24 trafficking protein 9	metal response element binding transcription factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Synaptic Vesicle Integral Component Of Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle Trans-Golgi Network Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Focal Adhesion ESC/E(Z) Complex
	Molecular Function	Protein Binding Syntaxin Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Corepressor Binding DNA Binding Chromatin Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Positive Regulation Of Organelle Organization Protein Exit From Endoplasmic Reticulum Early Endosome To Golgi Transport COPI Coating Of Golgi Vesicle	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Segment Specification Stem Cell Population Maintenance Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription By RNA Polymerase II Stem Cell Differentiation Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Histone H3-K27 Methylation Cellular Response To Leukemia Inhibitory Factor
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Bitter alcoholic beverage consumption ( 31046077) Chronotype ( 30696823) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Plasma clusterin levels ( 26545630) Response to lurasidone in schizophrenia ( 29730043) Triglyceride levels ( 32154731)
Interacting Genes		13 interacting genes: AQP9 CDC42 CKMT2 COPZ1 DDX54 ITM2A MTF2 NMT2 PLPPR2 SEC22A SEC23B THAP8 TMEM60	12 interacting genes: CDKN2D CREB1 GPRASP1 GSK3B KDM1A PIK3R3 PRKD2 PRMT6 SMAD3 SUV39H1 SUV39H2 TMED9
Entrez ID		54732	22823
HPRD ID		09975	14342
Ensembl ID		ENSG00000184840	ENSG00000143033
Uniprot IDs		A0A024R7M0 Q9BVK6	B4DZ69 B4DZG1 Q7Z534 Q9Y483
PDB IDs			5XFR
Enriched GO Terms of Interacting Partners?
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