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ADAMTSL4 and NOTCH2NLA
Data Source:
BioGRID
(two hybrid)
ADAMTSL4
NOTCH2NLA
Description
ADAMTS like 4
notch 2 N-terminal like A
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Interstitial Matrix
Endoplasmic Reticulum Lumen
Extracellular Matrix
Collagen-containing Extracellular Matrix
Extracellular Region
Cytoplasm
Molecular Function
Protease Binding
Metalloendopeptidase Activity
Protein Binding
Notch Binding
Calcium Ion Binding
Protein Binding
Biological Process
Epithelial Cell Development
Proteolysis
Apoptotic Process
Extracellular Matrix Organization
Positive Regulation Of Apoptotic Process
Notch Signaling Pathway
Cerebral Cortex Development
Cell Differentiation
Positive Regulation Of Notch Signaling Pathway
Pathways
Defective B3GALTL causes Peters-plus syndrome (PpS)
O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
Ectopia lentis
GWAS
Asthma (
32296059
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Coronary artery disease (
29212778
)
Cortical surface area (min-P) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (min-P) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Migraine (
27322543
)
Refractive error (
32231278
)
Rhegmatogenous retinal detachment (
23585552
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
209 interacting genes:
ADAM12
ADAMTSL5
ALPP
AMMECR1
APOL6
AQP1
ARNT2
ASPSCR1
ATG9A
BAG4
BANF2
BOLA2
BOLA2B
BRME1
CATSPER1
CBX3
CCDC26
CFAP206
CHCHD2
CHERP
CHIC2
CHRD
CHRNG
CLEC18A
COL8A1
CPNE7
CREB5
CST2
CTSB
CXCL16
CYP2S1
CYSRT1
DGCR6
DGCR6L
DIP2A
DLK2
DNPEP
DSCR8
EFEMP2
EIF4E2
EPDR1
ERCC3
EXOSC5
FAH
FAM124B
FARS2
FBLN1
FBXO17
FBXW5
FHL3
FKBP1B
FLNA
FRS3
GATA2
GIP
GLRX3
GLYCTK
GMCL2
GNE
GNG13
GNMT
GOLGA8EP
GSTP1
GUCD1
HEXIM2
HGF
HNRNPLL
HOXA1
HOXC8
HSD3B7
INS
IP6K1
ITGB2
ITGB4
JOSD1
KCTD7
KCTD9
KIF1A
KLHL38
KRTAP1-1
KRTAP1-5
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-3
KRTAP19-2
KRTAP21-2
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-7
KRTAP5-9
KRTAP6-2
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-4
LCE1A
LCE1B
LCE1C
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3A
LCE3C
LCE3D
LCE3E
LCE4A
LGALS14
LHX4
LINC00671
LMO1
LMO2
LMO4
LNX1
LONRF1
LRFN4
LRRC29
MAGOHB
MAPKBP1
MGAT5B
MID2
MKRN3
MORN3
MVP
MYLIP
MYO15B
NATD1
NBPF19
NEK8
NFKBID
NMUR2
NOTCH2NLA
NR4A3
NTAQ1
NTF4
NTN4
NUFIP2
OLFM3
OTX1
PCSK5
PID1
PIN1
PKN1
PLSCR1
PLSCR4
POLD1
POLR1C
POU4F2
PRKAB2
PRR19
PTGER3
PTPMT1
QPRT
R3HDM2
RAB2B
RCHY1
RGL2
RHOJ
RPS19BP1
RUNX1T1
SALL2
SCNM1
SHFL
SLC13A5
SLC23A1
SLC6A20
SLIT1
SMARCC1
SORBS3
SPATA8
SPINK2
SPRY1
SPRY2
STK16
SUSD6
TAPBPL
TCEA2
TFAP2D
TGFB1
THAP6
TMEM150A
TMSB4XP6
TOP3B
TRIM42
TRIM55
TRIM63
TRIP6
TSSK3
TUBGCP4
USP21
VASN
VENTX
VWC2
ZFHX2
ZNF330
ZNF414
ZNF417
ZNF587
357 interacting genes:
ACY3
ADAM12
ADAMTSL3
ADAMTSL4
ADAMTSL5
ADCK5
AGXT
ALDH16A1
ALDH3B1
ALPI
ALPP
ANKS1A
AQP1
AQP5
ARID3A
ASPSCR1
ATG9A
ATP5F1D
BCAM
BCL6B
BLCAP
BMP7
BRME1
C11orf87
C5orf60
CA6
CARHSP1
CATSPER1
CCDC26
CCDC93
CCER1
CD164
CDK5R1
CELF5
CERK
CHCHD3
CHDH
CHIC2
CHRD
CHRNG
CLDN2
CLEC18A
CNNM3
COL8A1
CRACR2A
CRCT1
CREB5
CRH
CRY2
CSF1
CST2
CST9L
CTNNBIP1
CTSG
CTSZ
CXCL16
CXCL5
CYHR1
CYP21A2
CYSRT1
DAGLB
DALRD3
DBH
DGCR6
DGKQ
DHRS1
DMRT3
DNAL4
DOCK2
DRD5
EFNA3
EIF4E2
ELANE
EMC7
EPHB6
ESR2
F10
FAAH
FADS2
FAM124B
FAM221A
FAM71C
FAM71E2
FAM74A4
FAM90A1
FARS2
FASLG
FBXL18
FBXW5
FOXB1
FRS3
FTHL17
FZD10
GABRD
GATA2
GEM
GFOD1
GIP
GLP1R
GLRX3
GLYAT
GNAI2
GNE
GNMT
GSTP1
GTF3C5
H2AC15
HAPLN2
HBA1
HBA2
HBZ
HCK
HHEX
HOXA1
HOXB9
HOXC8
HPCAL1
HSBP1
HSD3B7
HSPA12B
HSPBP1
HSPD1
ICAM4
IFI30
IL10
IL2RG
INO80B
INPP5D
INS
ITGB2
ITGB4
ITGB5
JOSD1
KCNS2
KCTD15
KIF1A
KLHL38
KLK8
KPRP
KRT20
KRT83
KRTAP10-1
KRTAP10-10
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP12-4
KRTAP13-2
KRTAP13-3
KRTAP13-4
KRTAP2-3
KRTAP2-4
KRTAP26-1
KRTAP3-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP4-7
KRTAP5-11
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-3
KRTAP9-4
KRTAP9-8
LCE1A
LCE1B
LCE1D
LCE1E
LCE1F
LCE2B
LCE2C
LCE2D
LCE3A
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LIMS2
LIN7A
LINC00526
LINC00656
LMNTD2
LMO2
LNX1
LONRF3
LRCH4
LRFN4
LYVE1
MACO1
MAPKBP1
MARK4
MATN3
MELTF
MFSD13A
MOS
MRGBP
MRPL40
MTA1
MVP
MXD3
MXI1
MYO15B
MYPOP
NAB2
NAXD
NECTIN2
NECTIN3
NEDD9
NEU2
NMU
NMUR2
NPBWR2
NPDC1
NPPB
NR1D2
NTM
NTN4
NUBP2
OLFM2
OTX1
P2RX4
P2RX7
P2RY6
PCED1A
PCED1B
PCSK5
PDE9A
PGAP6
PGLS
PHLDA1
PID1
PIGS
PLEKHN1
PLPP2
PLSCR4
POLR2G
POM121L8P
POMGNT2
PRF1
PRKAA2
PRPF31
PRPS2
PRR35
PSMA1
PSMG2
PTGER3
PTK7
PTPMT1
PTPN23
PVR
QPRT
R3HDM2
RAB3IL1
RAMP3
RASD1
RCHY1
RECK
RET
RGL2
RNF111
RPS19BP1
RPS28
RTN4RL1
SCNM1
SDCBP
SELENOM
SEMA3B
SEMA4C
SHFL
SLC22A23
SLC22A5
SLC23A1
SLC25A10
SLC25A6
SLC43A2
SLC5A5
SLC6A20
SMARCD2
SMARCE1
SMCP
SMOC1
SNAI1
SPATA24
SPATA8
SPG7
SPINK2
SPPL2C
SPRY1
STAC
STK16
TAPBPL
TBC1D10C
TBC1D16
TCAF1
TEDC2
THAP7
THEMIS2
TINAGL1
TLE5
TMEFF2
TMEM150A
TMEM231
TMEM41A
TMIE
TNIP3
TNK2
TNP2
TNS2
TRAPPC14
TRIM27
TRIM42
TROAP
TRPV6
TSPAN4
TTPA
TXNDC5
UBQLN4
UTP23
UXT
VASN
WDR25
WT1-AS
XCL2
YIPF3
ZDHHC1
ZFYVE21
ZNF124
ZNF319
ZNF32
ZNF330
ZNF408
ZNF414
ZNF417
ZNF439
ZNF440
ZNF446
ZNF497
ZNF580
ZNF581
ZNF587
ZNF648
ZNF672
ZNF688
ZNF786
ZNF837
Entrez ID
54507
388677
HPRD ID
18237
14833
Ensembl ID
ENSG00000143382
ENSG00000264343
Uniprot IDs
A0A669KBE7
B7ZMJ3
Q6UY14
Q9UFG7
P0DPK4
Q7Z3S9
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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