RAB4B and RABEP1

Data Source:
BioGRID (two hybrid)

		RAB4B	RABEP1
Description		RAB4B, member RAS oncogene family	rabaptin, RAB GTPase binding effector protein 1
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GO Annotations	Cellular Component	Endosome Plasma Membrane Secretory Granule Membrane Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome	Endosome Early Endosome Endocytic Vesicle Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	Molecular_function GTPase Activity Protein Binding GTP Binding	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Protein Transport Regulation Of Endocytosis Rab Protein Signal Transduction Neutrophil Degranulation Glucose Import	Golgi To Plasma Membrane Transport Endocytosis Apoptotic Process Signal Transduction Protein Transport Vesicle-mediated Transport Positive Regulation Of GTPase Activity Membrane Fusion Protein Localization To Ciliary Membrane
Pathways		Neutrophil degranulation RAB geranylgeranylation MET receptor recycling	TBC/RABGAPs
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Carotid intima media thickness (mean) ( 31801372) Chronic obstructive pulmonary disease ( 22080838 28166215) Emphysema imaging phenotypes ( 26030696) Eosinophil percentage of white cells ( 32888494) Hematocrit ( 32888494) Hemoglobin ( 32888494) Kawasaki disease ( 22081228) Red blood cell count ( 32888494) Smoking behaviour (cigarettes smoked per day) ( 30617275)	Body mass index ( 28892062 25673413) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494) Monocyte count ( 32888494) Red blood cell density in sickle cell anemia ( 28552477) White blood cell count ( 27863252)
Interacting Genes		9 interacting genes: BOLA2 BOLA2B CDC45 EXOC5 FAM71C RAB7A RABAC1 RABEP1 VPS52	58 interacting genes: ABI2 AIMP2 AP1G1 AP1G2 ATXN7 BARD1 CASP3 CCDC120 CCND1 CDC73 CDK18 CDKL3 CEP57 CFAP53 ELOA ESCO2 FAM50B FAM90A1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 LENG1 MAT2B MCRS1 ODAD3 PELI2 PKP2 PRPF3 RAB1A RAB33B RAB4A RAB4B RAB5A RABGEF1 RGS17 RNF39 SMURF1 SNAPIN SNW1 SRPK2 STAR TNS4 TRAPPC2L TRIM26 TSC2 TSHZ2 UBC UBTFL1 USP2 UTP14C WASHC3 YWHAG ZNF438 ZNF512B ZNF774
Entrez ID		53916	9135
HPRD ID		11473	04684
Ensembl ID		ENSG00000167578	ENSG00000029725
Uniprot IDs		A0A024R0K8 P61018	B4DMM4 Q15276
PDB IDs		2O52	1P4U 1TU3 1X79 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?
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