RABEP1 and CFAP53

Data Source:
BioGRID (two hybrid)

		RABEP1	CFAP53
Description		rabaptin, RAB GTPase binding effector protein 1	cilia and flagella associated protein 53
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Endocytic Vesicle Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Recycling Endosome	Cellular_component Extracellular Region Cilium
	Molecular Function	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Domain Specific Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Golgi To Plasma Membrane Transport Endocytosis Apoptotic Process Signal Transduction Protein Transport Vesicle-mediated Transport Positive Regulation Of GTPase Activity Membrane Fusion Protein Localization To Ciliary Membrane	Cilium Movement Determination Of Left/right Symmetry Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry
Pathways		TBC/RABGAPs
Drugs
Diseases
GWAS		Body mass index ( 28892062 25673413) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494) Monocyte count ( 32888494) Red blood cell density in sickle cell anemia ( 28552477) White blood cell count ( 27863252)
Interacting Genes		58 interacting genes: ABI2 AIMP2 AP1G1 AP1G2 ATXN7 BARD1 CASP3 CCDC120 CCND1 CDC73 CDK18 CDKL3 CEP57 CFAP53 ELOA ESCO2 FAM50B FAM90A1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 LENG1 MAT2B MCRS1 ODAD3 PELI2 PKP2 PRPF3 RAB1A RAB33B RAB4A RAB4B RAB5A RABGEF1 RGS17 RNF39 SMURF1 SNAPIN SNW1 SRPK2 STAR TNS4 TRAPPC2L TRIM26 TSC2 TSHZ2 UBC UBTFL1 USP2 UTP14C WASHC3 YWHAG ZNF438 ZNF512B ZNF774	29 interacting genes: APP CBY1 CCDC57 CCDC85B CCHCR1 CCNC CEP70 CWF19L2 GAS8 GRIPAP1 HIP1 HMG20A KRT31 KRT34 LDOC1 LENG8 MYOG PARVG PIBF1 PNMA1 RABEP1 SH2D4A TBC1D21 TEX11 TNIP1 TRIM23 TRIM54 TXLNA TXLNB
Entrez ID		9135	220136
HPRD ID		04684	09958
Ensembl ID		ENSG00000029725	ENSG00000172361
Uniprot IDs		B4DMM4 Q15276	Q96M91
PDB IDs		1P4U 1TU3 1X79 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?
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