PLXNB3 and CUL7

Data Source:
HPRD (two hybrid)

		PLXNB3	CUL7
Description		plexin B3	cullin 7
Image		No pdb structure
GO Annotations	Cellular Component	Semaphorin Receptor Complex Plasma Membrane Integral Component Of Plasma Membrane Cell Surface	Anaphase-promoting Complex Cytoplasm Golgi Apparatus Centrosome Cytosol Cullin-RING Ubiquitin Ligase Complex Cul7-RING Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm 3M Complex
	Molecular Function	Protein Binding Semaphorin Receptor Activity Protein Domain Specific Binding Rho GDP-dissociation Inhibitor Binding Cell-cell Adhesion Mediator Activity	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Cell Adhesion Regulation Of Cell Shape Negative Regulation Of Lamellipodium Assembly Positive Regulation Of Neuron Projection Development Regulation Of Cell Migration Negative Regulation Of Cell Migration Negative Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Positive Chemotaxis Cell Chemotaxis Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance	Microtubule Cytoskeleton Organization Mitotic Cytokinesis Vasculogenesis Epithelial To Mesenchymal Transition Placenta Development Proteolysis Ubiquitin-dependent Protein Catabolic Process Golgi Organization Regulation Of Mitotic Nuclear Division Viral Process Protein Ubiquitination IRE1-mediated Unfolded Protein Response Post-translational Protein Modification Positive Regulation Of Dendrite Morphogenesis
Pathways		Other semaphorin interactions	XBP1(S) activates chaperone genes Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases			3M syndrome
GWAS
Interacting Genes		8 interacting genes: ARHGEF11 BTBD3 CUL7 CUL9 MAGI2 MAGI3 RIT2 SPOCK2	9 interacting genes: COMMD1 FBXW8 MEGF10 MTDH MTNR1A PLXNB3 RBX1 SKP1 UBE2M
Entrez ID		5365	9820
HPRD ID		02198	09901
Ensembl ID		ENSG00000198753	ENSG00000044090
Uniprot IDs		A8K920 Q9ULL4	Q14999
PDB IDs			2JNG
Enriched GO Terms of Interacting Partners?
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