PLXNB3 and CUL9

Data Source:
HPRD (two hybrid)

		PLXNB3	CUL9
Description		plexin B3	cullin 9
Image		No pdb structure
GO Annotations	Cellular Component	Semaphorin Receptor Complex Plasma Membrane Integral Component Of Plasma Membrane Cell Surface	Cytosol Cullin-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Semaphorin Receptor Activity Protein Domain Specific Binding Rho GDP-dissociation Inhibitor Binding Cell-cell Adhesion Mediator Activity	Protein Binding ATP Binding Transferase Activity Ubiquitin Protein Ligase Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Cell Adhesion Regulation Of Cell Shape Negative Regulation Of Lamellipodium Assembly Positive Regulation Of Neuron Projection Development Regulation Of Cell Migration Negative Regulation Of Cell Migration Negative Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Positive Chemotaxis Cell Chemotaxis Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance	Microtubule Cytoskeleton Organization Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Nuclear Division Protein Ubiquitination Post-translational Protein Modification
Pathways		Other semaphorin interactions	Neddylation
Drugs
Diseases
GWAS			Adult hearing difficulty ( 31564434) General risk tolerance (MTAG) ( 30643258) Obesity-related traits ( 23251661) Tea consumption ( 31046077)
Interacting Genes		8 interacting genes: ARHGEF11 BTBD3 CUL7 CUL9 MAGI2 MAGI3 RIT2 SPOCK2	8 interacting genes: CYCS MTDH PLXNB3 TP53 UBE2E2 UBE2G1 UBE2G2 UBE2L3
Entrez ID		5365	23113
HPRD ID		02198	06317
Ensembl ID		ENSG00000198753	ENSG00000112659
Uniprot IDs		A8K920 Q9ULL4	Q8IWT3
PDB IDs			2JUF
Enriched GO Terms of Interacting Partners?
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