PLXNB3 and SPOCK2

Data Source:
HPRD (two hybrid)

		PLXNB3	SPOCK2
Description		plexin B3	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Semaphorin Receptor Complex Plasma Membrane Integral Component Of Plasma Membrane Cell Surface	Extracellular Matrix
	Molecular Function	Protein Binding Semaphorin Receptor Activity Protein Domain Specific Binding Rho GDP-dissociation Inhibitor Binding Cell-cell Adhesion Mediator Activity	Calcium Ion Binding Protein Binding Glycosaminoglycan Binding Metalloendopeptidase Inhibitor Activity Extracellular Matrix Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Cell Adhesion Regulation Of Cell Shape Negative Regulation Of Lamellipodium Assembly Positive Regulation Of Neuron Projection Development Regulation Of Cell Migration Negative Regulation Of Cell Migration Negative Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Positive Chemotaxis Cell Chemotaxis Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance	Synapse Assembly Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of Endopeptidase Activity Peptide Cross-linking Via Chondroitin 4-sulfate Glycosaminoglycan Extracellular Matrix Organization Regulation Of Cell Differentiation Cellular Response To Leukemia Inhibitory Factor Positive Regulation Of Cell Motility
Pathways		Other semaphorin interactions
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Insulin-like growth factors ( 21216879) Smoking behavior ( 22832964)
Interacting Genes		8 interacting genes: ARHGEF11 BTBD3 CUL7 CUL9 MAGI2 MAGI3 RIT2 SPOCK2	3 interacting genes: PLXNB3 SPOCK3 TES
Entrez ID		5365	9806
HPRD ID		02198	12146
Ensembl ID		ENSG00000198753	ENSG00000107742
Uniprot IDs		A8K920 Q9ULL4	A0A024QZQ5 Q92563
PDB IDs
Enriched GO Terms of Interacting Partners?
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