PLXNB3 and BTBD3

Data Source:
HPRD (two hybrid)

		PLXNB3	BTBD3
Description		plexin B3	BTB domain containing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Semaphorin Receptor Complex Plasma Membrane Integral Component Of Plasma Membrane Cell Surface	Nucleus Cytosol
	Molecular Function	Protein Binding Semaphorin Receptor Activity Protein Domain Specific Binding Rho GDP-dissociation Inhibitor Binding Cell-cell Adhesion Mediator Activity	Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Cell Adhesion Regulation Of Cell Shape Negative Regulation Of Lamellipodium Assembly Positive Regulation Of Neuron Projection Development Regulation Of Cell Migration Negative Regulation Of Cell Migration Negative Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Positive Chemotaxis Cell Chemotaxis Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance	Cerebral Cortex Development Neurogenesis Dendrite Morphogenesis
Pathways		Other semaphorin interactions
Drugs
Diseases
GWAS			Benign prostatic hyperplasia ( 30988330) Cardiac hypertrophy ( 21348951) Cognitive decline rate in late mild cognitive impairment ( 26252872) Diastolic blood pressure ( 30224653) Hearing function ( 25060954) Intraocular pressure ( 29785010) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Serum metabolite ratios in chronic kidney disease ( 29545352)
Interacting Genes		8 interacting genes: ARHGEF11 BTBD3 CUL7 CUL9 MAGI2 MAGI3 RIT2 SPOCK2	10 interacting genes: BTBD6 CDC37 CUL3 GORASP2 MEOX2 PLXNB3 RNF4 SUMO1 TEPSIN UBE2I
Entrez ID		5365	22903
HPRD ID		02198	12538
Ensembl ID		ENSG00000198753	ENSG00000132640
Uniprot IDs		A8K920 Q9ULL4	B4DK27 B4DRI6 Q9Y2F9
PDB IDs
Enriched GO Terms of Interacting Partners?
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