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PLN and MTIF3
Data Source:
BioGRID
(two hybrid)
PLN
MTIF3
Description
phospholamban
mitochondrial translational initiation factor 3
Image
GO Annotations
Cellular Component
Mitochondrion
Endoplasmic Reticulum
Membrane
Mitochondrial Membrane
Vesicle
Sarcoplasmic Reticulum Membrane
Perinuclear Region Of Cytoplasm
Calcium Ion-transporting ATPase Complex
Mitochondrion
Molecular Function
Enzyme Inhibitor Activity
Protein Binding
ATPase Inhibitor Activity
Identical Protein Binding
Protein Homodimerization Activity
ATPase Binding
Translation Initiation Factor Activity
Protein Binding
Translation Factor Activity, RNA Binding
Ribosome Binding
Ribosomal Small Subunit Binding
Biological Process
Regulation Of The Force Of Heart Contraction
Calcium Ion Transport
Notch Signaling Pathway
Blood Circulation
Regulation Of Heart Contraction
Response To Zinc Ion
Negative Regulation Of Heart Rate
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Negative Regulation Of ATPase Activity
Response To Insulin
Response To Testosterone
Negative Regulation Of Catalytic Activity
Cardiac Muscle Tissue Development
Regulation Of Cytosolic Calcium Ion Concentration
Regulation Of Calcium Ion Transport
Negative Regulation Of Calcium Ion Transport
Relaxation Of Cardiac Muscle
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Regulation Of Cardiac Muscle Cell Contraction
Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process
Regulation Of Cardiac Muscle Cell Membrane Potential
Regulation Of The Force Of Heart Contraction By Cardiac Conduction
Negative Regulation Of Calcium Ion Import
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Negative Regulation Of Calcium Ion Binding
Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity
Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity
Regulation Of Relaxation Of Cardiac Muscle
Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum
Ribosome Disassembly
Mitochondrial Translational Initiation
Pathways
Ion homeostasis
Ion transport by P-type ATPases
Mitochondrial translation initiation
Drugs
Diseases
GWAS
Atrial fibrillation (
28416818
30061737
)
Cardiac structure and function (
19584346
)
QRS complex (Sokolow-Lyon) (
27659466
)
QRS duration (
27577874
27659466
)
QT interval (
23166209
24952745
19305408
19305409
19587794
29874175
)
Resting heart rate (
27798624
)
Adult body size (
32376654
)
BMI (adjusted for smoking behaviour) (
28443625
)
Body mass index (
28892062
25673413
20935630
)
Body mass index (joint analysis main effects and smoking interaction) (
28443625
)
Estimated glomerular filtration rate change in renal transplantation (recipient effect) (
30920136
)
Night sleep phenotypes (
27126917
)
Psychosis proneness (hypomanic personality scale and perceptual aberration scale) (
28525603
)
Interacting Genes
64 interacting genes:
ARL13B
ASGR2
ATP2A1
ATP2A2
ATP6V0E1
BCL2L13
BIK
CD53
CLDN7
CLEC2D
CPLX4
CREB3
CREB3L1
DMPK
DVL3
EDA
ELOVL4
FAM209A
FKBP8
FNDC9
GJA8
GPR152
GPR37L1
GPX8
HIBADH
HSD17B13
KIR2DL3
LDLRAD1
LSMEM2
MFF
MFSD5
MGST2
MGST3
MS4A7
MTIF3
MUC1
PLPPR1
PPP1R3A
PRKACA
RTN3
S100A1
SAR1A
SDC3
SIT1
SLC14A2
SLC30A8
SLC34A2
SLC35C2
SLC39A2
SLN
SPACA1
SPAG4
STX1A
STX2
TMEM106C
TMEM179B
TMEM205
TMEM31
TMEM45A
TMEM45B
TMEM52B
TMEM79
TMEM86B
TMPRSS2
84 interacting genes:
APOD
BCL2L1
BMP10
BPIFA1
BRICD5
CABP7
CD47
CDIPT
CDS2
CGRRF1
CLDND2
CLEC7A
CMTM5
COL4A5
COQ8A
CTXN3
CXCL9
CYBC1
CYP4F2
EPGN
FBXO7
FETUB
FXYD3
FXYD6-FXYD2
HSFX1
HSFX2
HTATIP2
ITGB2
JAGN1
LAPTM4B
LAT
LDLR
LHFPL5
MAPK1
MGST3
MRFAP1
MS4A1
NAT8
NDRG4
ORMDL3
PAXIP1
PEA15
PLN
PLP1
PRH1
RPRM
SCD
SELENOK
SERP1
SERP2
SERTM1
SIAH1
SNX2
SPANXN2
STARD4
STATH
STRIT1
STX3
STX6
THBD
THSD7B
TMED8
TMEM109
TMEM11
TMEM128
TMEM147
TMEM176A
TMEM218
TMEM239
TMEM242
TMEM243
TMEM254
TMEM42
TMEM97
TRARG1
TSPAN33
TUFM
UNC50
VAMP4
VEZT
VKORC1L1
YIPF6
ZDHHC15
ZNF202
Entrez ID
5350
219402
HPRD ID
01395
17609
Ensembl ID
ENSG00000198523
ENSG00000122033
Uniprot IDs
P26678
Q5R352
Q9H2K0
PDB IDs
1K9N
1KCH
1PLN
1PLP
1PSL
1ZLL
2HYN
6NEQ
6NF8
6RW4
6RW5
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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