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PLN and GPR152
Data Source:
BioGRID
(two hybrid)
PLN
GPR152
Description
phospholamban
G protein-coupled receptor 152
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Endoplasmic Reticulum
Membrane
Mitochondrial Membrane
Vesicle
Sarcoplasmic Reticulum Membrane
Perinuclear Region Of Cytoplasm
Calcium Ion-transporting ATPase Complex
Plasma Membrane
Integral Component Of Membrane
Molecular Function
Enzyme Inhibitor Activity
Protein Binding
ATPase Inhibitor Activity
Identical Protein Binding
Protein Homodimerization Activity
ATPase Binding
G Protein-coupled Receptor Activity
Protein Binding
Identical Protein Binding
Biological Process
Regulation Of The Force Of Heart Contraction
Calcium Ion Transport
Notch Signaling Pathway
Blood Circulation
Regulation Of Heart Contraction
Response To Zinc Ion
Negative Regulation Of Heart Rate
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Negative Regulation Of ATPase Activity
Response To Insulin
Response To Testosterone
Negative Regulation Of Catalytic Activity
Cardiac Muscle Tissue Development
Regulation Of Cytosolic Calcium Ion Concentration
Regulation Of Calcium Ion Transport
Negative Regulation Of Calcium Ion Transport
Relaxation Of Cardiac Muscle
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Regulation Of Cardiac Muscle Cell Contraction
Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process
Regulation Of Cardiac Muscle Cell Membrane Potential
Regulation Of The Force Of Heart Contraction By Cardiac Conduction
Negative Regulation Of Calcium Ion Import
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Negative Regulation Of Calcium Ion Binding
Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity
Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity
Regulation Of Relaxation Of Cardiac Muscle
Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum
G Protein-coupled Receptor Signaling Pathway
Pathways
Ion homeostasis
Ion transport by P-type ATPases
Drugs
Diseases
GWAS
Atrial fibrillation (
28416818
30061737
)
Cardiac structure and function (
19584346
)
QRS complex (Sokolow-Lyon) (
27659466
)
QRS duration (
27577874
27659466
)
QT interval (
23166209
24952745
19305408
19305409
19587794
29874175
)
Resting heart rate (
27798624
)
Non-response to citalopram or escitalopram and depression (
27622933
)
Refractive error (
32231278
)
Interacting Genes
64 interacting genes:
ARL13B
ASGR2
ATP2A1
ATP2A2
ATP6V0E1
BCL2L13
BIK
CD53
CLDN7
CLEC2D
CPLX4
CREB3
CREB3L1
DMPK
DVL3
EDA
ELOVL4
FAM209A
FKBP8
FNDC9
GJA8
GPR152
GPR37L1
GPX8
HIBADH
HSD17B13
KIR2DL3
LDLRAD1
LSMEM2
MFF
MFSD5
MGST2
MGST3
MS4A7
MTIF3
MUC1
PLPPR1
PPP1R3A
PRKACA
RTN3
S100A1
SAR1A
SDC3
SIT1
SLC14A2
SLC30A8
SLC34A2
SLC35C2
SLC39A2
SLN
SPACA1
SPAG4
STX1A
STX2
TMEM106C
TMEM179B
TMEM205
TMEM31
TMEM45A
TMEM45B
TMEM52B
TMEM79
TMEM86B
TMPRSS2
194 interacting genes:
-
ABCG4
ABHD16A
ACSF2
ADIPOQ
AGTRAP
AIG1
ANKRD46
APOL3
AQP10
AQP3
AQP6
ARL6IP1
ARV1
ATP6V0C
B3GNT7
BDNF
BET1
BMP10
BNIP2
BNIP3
C14orf180
C1QL4
C8A
CCDC167
CCL4
CCL4L2
CD53
CD72
CD81
CDIPT
CDS2
CGRRF1
CLDND2
CLEC17A
CLEC1A
CLN5
CNIH1
COL8A2
COMT
CRISP3
CSGALNACT2
CTXN3
CYB561
CYB561A3
CYB5B
CYB5R3
CYBC1
DEFB108B
DGAT2L6
EBP
EDDM3B
EFNA5
EMD
ERG28
FA2H
FAM20B
FAXDC2
FDFT1
FUNDC2
FXYD3
FXYD6-FXYD2
GAST
GJB2
GOLT1A
GOLT1B
GOSR2
GPR151
GPR37L1
HHATL
HMOX1
HMOX2
IFNA8
IGF2
IGFBP5
IL1RL1
INS-IGF2
INSIG2
JAGN1
KCNA1
KCNN4
LAMB1
LAT
LEPROTL1
LHFPL2
LHFPL5
LTC4S
MAL
MAL2
MFF
MFSD5
MFSD6
MGLL
MGST3
MMD
MOSPD3
MS4A13
MYADML2
NAT8
NDUFB11
NEU1
NINJ2
NIPAL4
ORMDL1
ORMDL3
PEDS1-UBE2V1
PEX16
PGAP2
PIGF
PIN1
PLN
PNLIPRP1
PRAF2
PROM2
PTPRN
RABAC1
RBFA
REEP6
ROBO2
RTN3
RTP2
SACM1L
SCAMP4
SCD
SEC22B
SERF1A
SERF1B
SERP2
SFT2D2
SFTPC
SLC10A1
SLC13A4
SLC29A2
SLC30A3
SLC35A4
SLC35B1
SLC35B4
SLC35C2
SLC35F6
SLC38A1
SLC38A7
SLC39A2
SLC41A1
SLC66A1
SLC66A2
SLC7A1
SMCO4
STATH
STX1B
STX3
STX4
STX5
STX8
SYT15
TAP1
TEX264
TFRC
THSD7B
TIMMDC1
TM4SF19
TMEM100
TMEM120B
TMEM128
TMEM140
TMEM14B
TMEM14C
TMEM201
TMEM208
TMEM218
TMEM236
TMEM237
TMEM243
TMEM254
TMEM42
TMEM50B
TMEM54
TMEM60
TMEM97
TMPPE
TNFRSF10C
TSNARE1
TSPAN33
TSPAN7
TSPO2
UBIAD1
UNC50
VAMP1
VAMP4
VAMP5
VKORC1
YIPF1
YIPF4
YIPF6
ZDHHC15
Entrez ID
5350
390212
HPRD ID
01395
13599
Ensembl ID
ENSG00000198523
ENSG00000175514
Uniprot IDs
P26678
Q5R352
A0A0I9RJ67
Q8TDT2
PDB IDs
1K9N
1KCH
1PLN
1PLP
1PSL
1ZLL
2HYN
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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