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MTIF3 and CLEC7A
Data Source:
BioGRID
(two hybrid)
MTIF3
CLEC7A
Description
mitochondrial translational initiation factor 3
C-type lectin domain containing 7A
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Cytoplasm
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Molecular Function
Translation Initiation Factor Activity
Protein Binding
Translation Factor Activity, RNA Binding
Ribosome Binding
Ribosomal Small Subunit Binding
(1->3)-beta-D-glucan Binding
Protein Binding
Carbohydrate Binding
Pattern Recognition Receptor Activity
MHC Protein Binding
Metal Ion Binding
Biological Process
Ribosome Disassembly
Mitochondrial Translational Initiation
Leukocyte Activation Involved In Immune Response
Positive Regulation Of Dendritic Cell Cytokine Production
Phagocytosis, Recognition
Inflammatory Response
Cell Recognition
Positive Regulation Of Cell Population Proliferation
Carbohydrate Mediated Signaling
Positive Regulation Of Gene Expression
Detection Of Fungus
Positive Regulation Of Cell Migration
Positive Regulation Of Protein-containing Complex Assembly
Detection Of Molecule Of Fungal Origin
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Superoxide Anion Generation
T Cell Activation
Defense Response To Protozoan
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Innate Immune Response
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Phagocytosis
Positive Regulation Of Lymphocyte Activation
Positive Regulation Of Killing Of Cells Of Other Organism
Positive Regulation Of Respiratory Burst
Cellular Response To Molecule Of Fungal Origin
Positive Regulation Of Monocyte Chemotactic Protein-1 Production
Positive Regulation Of Wound Healing
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Cell Maturation
Pathways
Mitochondrial translation initiation
CLEC7A (Dectin-1) signaling
CLEC7A (Dectin-1) signaling
Drugs
Diseases
Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS
Adult body size (
32376654
)
BMI (adjusted for smoking behaviour) (
28443625
)
Body mass index (
28892062
25673413
20935630
)
Body mass index (joint analysis main effects and smoking interaction) (
28443625
)
Estimated glomerular filtration rate change in renal transplantation (recipient effect) (
30920136
)
Night sleep phenotypes (
27126917
)
Psychosis proneness (hypomanic personality scale and perceptual aberration scale) (
28525603
)
Interacting Genes
84 interacting genes:
APOD
BCL2L1
BMP10
BPIFA1
BRICD5
CABP7
CD47
CDIPT
CDS2
CGRRF1
CLDND2
CLEC7A
CMTM5
COL4A5
COQ8A
CTXN3
CXCL9
CYBC1
CYP4F2
EPGN
FBXO7
FETUB
FXYD3
FXYD6-FXYD2
HSFX1
HSFX2
HTATIP2
ITGB2
JAGN1
LAPTM4B
LAT
LDLR
LHFPL5
MAPK1
MGST3
MRFAP1
MS4A1
NAT8
NDRG4
ORMDL3
PAXIP1
PEA15
PLN
PLP1
PRH1
RPRM
SCD
SELENOK
SERP1
SERP2
SERTM1
SIAH1
SNX2
SPANXN2
STARD4
STATH
STRIT1
STX3
STX6
THBD
THSD7B
TMED8
TMEM109
TMEM11
TMEM128
TMEM147
TMEM176A
TMEM218
TMEM239
TMEM242
TMEM243
TMEM254
TMEM42
TMEM97
TRARG1
TSPAN33
TUFM
UNC50
VAMP4
VEZT
VKORC1L1
YIPF6
ZDHHC15
ZNF202
47 interacting genes:
ADAM33
AIP
ARL13B
ASGR2
BNIP3
BNIP3L
C14orf180
CALM3
CD53
CD74
CTXN3
CXCL9
FAM3A
FCGR1A
FNDC9
GJB1
HSPD1
IFNGR2
IL1RL1
JAGN1
KLRC1
KTN1
MTIF3
NEMP1
NINJ2
NSG2
OCLN
OLFM4
OPRM1
PTTG1IP
RANBP9
RHOU
SAR1A
SEC22A
SGCB
SMIM3
SPINT1
SUSD3
SYNE4
TEX29
TLCD4
TMEM79
TMPRSS2
TMPRSS4
UPK2
VSIR
ZFPL1
Entrez ID
219402
64581
HPRD ID
17609
08396
Ensembl ID
ENSG00000122033
ENSG00000172243
Uniprot IDs
Q9H2K0
A0A024RAN9
A0A0S2Z5Q1
Q68D78
Q9BXN2
PDB IDs
6NEQ
6NF8
6RW4
6RW5
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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