ATP6V1E1 and ATP6V1G1

Data Source:
BioGRID (biochemical)
HPRD (two hybrid)

		ATP6V1E1	ATP6V1G1
Description		ATPase H+ transporting V1 subunit E1	ATPase H+ transporting V1 subunit G1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Cytosol Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting Two-sector ATPase Complex, Catalytic Domain Extracellular Exosome	Lysosomal Membrane Cytosol Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Extracellular Exosome
	Molecular Function	Protein Binding Proton-exporting ATPase Activity, Phosphorylative Mechanism Hydrolase Activity Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding	Protein Binding ATPase Activity Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Cellular Response To Increased Oxygen Levels Phagosome Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid	Tiludronic acid
Diseases
GWAS			Bone mineral density (hip) and age at menarche ( 26312577) Bone mineral density (spine) and age at menarche ( 26312577)
Interacting Genes		14 interacting genes: ALDOA ALDOB ALDOC APP ATP6V0E1 ATP6V1G1 ATP6V1G2 ATP6V1H HSPB2 MESD SLC9A3R1 SOS1 TRAF6 XRCC6	13 interacting genes: AP2B1 APP ATP6V1E1 ATP6V1E2 BCL2L11 GOLGA2 GOLGA6L9 GORASP2 LDOC1 LHX3 MAGEA6 NTAQ1 PNMA1
Entrez ID		529	9550
HPRD ID		00163	06294
Ensembl ID		ENSG00000131100	ENSG00000136888
Uniprot IDs		P36543 Q53Y06	A0A024R883 O75348
PDB IDs
Enriched GO Terms of Interacting Partners?
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