AP1B1 and PSORS1C2

Data Source:
BioGRID (two hybrid)

		AP1B1	PSORS1C2
Description		adaptor related protein complex 1 subunit beta 1	psoriasis susceptibility 1 candidate 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Cellular_component Extracellular Region
	Molecular Function	Protein Binding Protein Kinase Binding Clathrin Binding	Molecular_function Protein Binding
	Biological Process	Kidney Development Intracellular Protein Transport Determination Of Left/right Symmetry Heart Development Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus	Biological_process
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Carotid atherosclerosis in HIV infection ( 20009918) Heel bone mineral density ( 30598549 28869591) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Pancreatic cancer ( 25086665) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Broad depression or schizophrenia ( 30626913) Height ( 28552196 25282103) Hematology traits ( 23263863) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Metabolite levels ( 23823483) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Night sleep phenotypes ( 27126917) Serum uric acid levels ( 30993211) Ulcerative colitis ( 28067908) White blood cell count ( 21738480)
Interacting Genes		43 interacting genes: AGR3 AP1G1 AP1G2 AP1M2 ARF1 ARF5 ARF6 ARRB2 ATF7IP ATM ATR BARD1 BUB1 BUB1B CLTC CREBBP CRYBB1 FARS2 FMNL2 FNDC11 GPANK1 GTF2I KIF13A LDLRAP1 MLH1 MSGN1 MTNR1B MYG1 NECAP1 NTRK2 NUP54 PIP5K1C POM121 PRKDC PSORS1C2 RNF39 SHBG SLC2A8 SMAD2 TBC1D22B TSGA10IP U2AF1 U2AF1L5	27 interacting genes: AGR2 AP1B1 AP2B1 BANP CEP70 ERICH2 EVPL GUCA1C HMG20A HOMER3 LHX3 MED20 MEIS3 MYL2 MYL7 NCKIPSD PAX6 PEX19 REL RTRAF SERTAD1 SGTA SGTB TTC23 UBQLN1 UBQLN2 VASP
Entrez ID		162	170680
HPRD ID		02541	17921
Ensembl ID		ENSG00000100280	ENSG00000204538
Uniprot IDs		Q10567	A0A1U9X9A6 Q9UIG4
PDB IDs		4HMY 4P6Z 6CM9 6CRI 6D83 6D84 6DFF
Enriched GO Terms of Interacting Partners?
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