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SERPINB9 and GZMB
Data Source:
HPRD
(in vitro)
SERPINB9
GZMB
Description
serpin family B member 9
granzyme B
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Membrane
Collagen-containing Extracellular Matrix
Extracellular Exosome
Immunological Synapse
Extracellular Region
Nucleus
Cytoplasm
Mitochondrion
Cytosol
Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
Protease Binding
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Serine-type Endopeptidase Activity
Protein Binding
Serine-type Peptidase Activity
Biological Process
Mast Cell Mediated Immunity
Apoptotic Process
Immune Response
Response To Bacterium
Positive Regulation Of Gene Expression
Negative Regulation Of Endopeptidase Activity
Negative Regulation By Symbiont Of Host Apoptotic Process
Protection From Natural Killer Cell Mediated Cytotoxicity
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cellular Response To Estrogen Stimulus
Apoptotic Process
Negative Regulation Of Translation
Cytolysis
Natural Killer Cell Mediated Cytotoxicity
Proteolysis Involved In Cellular Protein Catabolic Process
Pyroptosis
Granzyme-mediated Programmed Cell Death Signaling Pathway
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways
NOTCH2 intracellular domain regulates transcription
Activation, myristolyation of BID and translocation to mitochondria
Drugs
Raloxifene
Diseases
GWAS
Plateletcrit (
32888494
)
Vitiligo (
27723757
)
Blood protein levels (
30072576
29875488
)
Emphysema annual change measurement in smokers (adjusted lung density) (
31324189
)
Vitiligo (
20410501
27723757
)
Interacting Genes
28 interacting genes:
BRD7
CASP1
CASP4
CCDC90B
COPS6
CRMP1
ECH1
EEF1A1
ERG28
GAPDH
GBP2
GDF9
GZMB
IGSF21
LRIF1
MED31
PLEKHM1
PRPF40A
RBM48
SETDB1
TLE1
TP53
TRAF5
TUBB2A
UBR1
UNC119
XRCC6
ZHX1
26 interacting genes:
BID
CASP3
CASP7
CASP8
CASP9
CD2AP
CHRM3
DFFA
GRIA3
IGF2R
LMNA
LMNB1
PARP1
PRF1
PRKDC
PTGES3
PTK2
RAB27A
SERPINB9
SRGN
TUBA1A
UBE4A
UBE4B
XRCC4
XRCC5
XRCC6
Entrez ID
5272
3002
HPRD ID
03480
00476
Ensembl ID
ENSG00000170542
ENSG00000100453
Uniprot IDs
A0A024QZT4
P50453
J3KQ52
P10144
Q67BC3
Q6XGZ4
PDB IDs
1FQ3
1IAU
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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