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SERPINB9 and CASP4
Data Source:
BioGRID
(pull down)
HPRD
(in vivo)
SERPINB9
CASP4
Description
serpin family B member 9
caspase 4
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Membrane
Collagen-containing Extracellular Matrix
Extracellular Exosome
Extracellular Region
Cytoplasm
Mitochondrion
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
Plasma Membrane
Protein-containing Complex
IPAF Inflammasome Complex
NLRP3 Inflammasome Complex
AIM2 Inflammasome Complex
Molecular Function
Protease Binding
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Cysteine-type Endopeptidase Activity
Protein Binding
CARD Domain Binding
Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis
Biological Process
Mast Cell Mediated Immunity
Apoptotic Process
Immune Response
Response To Bacterium
Positive Regulation Of Gene Expression
Negative Regulation Of Endopeptidase Activity
Negative Regulation By Symbiont Of Host Apoptotic Process
Protection From Natural Killer Cell Mediated Cytotoxicity
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cellular Response To Estrogen Stimulus
Proteolysis
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Inflammatory Response
Protein Autoprocessing
Regulation Of Apoptotic Process
Innate Immune Response
Regulation Of Inflammatory Response
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Pyroptosis
Intrinsic Apoptotic Signaling Pathway
Execution Phase Of Apoptosis
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Cellular Response To Amyloid-beta
Pathways
NOD1/2 Signaling Pathway
Drugs
Raloxifene
Incadronic acid
Diseases
GWAS
Plateletcrit (
32888494
)
Vitiligo (
27723757
)
Major depressive disorder (
29317602
)
Interacting Genes
28 interacting genes:
BRD7
CASP1
CASP4
CCDC90B
COPS6
CRMP1
ECH1
EEF1A1
ERG28
GAPDH
GBP2
GDF9
GZMB
IGSF21
LRIF1
MED31
PLEKHM1
PRPF40A
RBM48
SETDB1
TLE1
TP53
TRAF5
TUBB2A
UBR1
UNC119
XRCC6
ZHX1
16 interacting genes:
APAF1
APP
CASP10
CASP14
CASP3
CASP8
DSP
ELF4
IL18
IL1B
IL37
MYH9
NOD1
PLA2G4A
PSEN1
SERPINB9
Entrez ID
5272
837
HPRD ID
03480
04047
Ensembl ID
ENSG00000170542
ENSG00000196954
Uniprot IDs
A0A024QZT4
P50453
P49662
PDB IDs
6KMZ
6NRY
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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