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SERPINB5 and GSTO1
Data Source:
BioGRID
(two hybrid)
SERPINB5
GSTO1
Description
serpin family B member 5
glutathione S-transferase omega 1
Image
GO Annotations
Cellular Component
Extracellular Space
Cytoplasm
Nucleoplasm
Cytoplasm
Cytosol
Extracellular Exosome
Molecular Function
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Glutathione Transferase Activity
Protein Binding
Oxidoreductase Activity
Glutathione Dehydrogenase (ascorbate) Activity
Methylarsonate Reductase Activity
Biological Process
Morphogenesis Of An Epithelium
Negative Regulation Of Endopeptidase Activity
Extracellular Matrix Organization
Regulation Of Epithelial Cell Proliferation
Prostate Gland Morphogenesis
Glutathione Metabolic Process
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Positive Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion
L-ascorbic Acid Metabolic Process
Methylation
Interleukin-12-mediated Signaling Pathway
Xenobiotic Catabolic Process
Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Cellular Response To Arsenic-containing Substance
Cellular Oxidant Detoxification
Glutathione Derivative Biosynthetic Process
Pathways
Methylation
Glutathione conjugation
Vitamin C (ascorbate) metabolism
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
S,S-(2-Hydroxyethyl)Thiocysteine
Glutathione
Diseases
GWAS
Adverse response to chemotherapy in breast cancer (alopecia) (anti-microtubule) (
24025145
)
Blood protein levels (
30072576
29875488
)
Metabolite levels (
23823483
)
Interacting Genes
26 interacting genes:
AKT1
ATIC
BASP1
BCAR3
CASP8
COL1A2
EEF1A1
ESR1
GOLGA4
GSTO1
HDAC1
HSP90AA1
HSP90AB1
HSPA5
KRAS
LRRFIP1
MDH1
MT1H
PALB2
PPIF
SMAD4
STK11
TBP
TKT
UCHL5
XRCC3
8 interacting genes:
APP
CEP126
EEF1G
HSPB1
KAT5
RBM48
SERPINB5
SETDB1
Entrez ID
5268
9446
HPRD ID
01111
10401
Ensembl ID
ENSG00000206075
ENSG00000148834
Uniprot IDs
A0A024R2B6
P36952
P78417
V9HWG9
PDB IDs
1WZ9
1XQG
1XQJ
1XU8
1EEM
3LFL
3VLN
4IS0
4YQM
4YQU
4YQV
5UEH
5V3Q
5YVN
5YVO
6MHB
6MHC
6MHD
6PNM
6PNN
6PNO
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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