SERPINB5 and TKT

Data Source:
BioGRID (two hybrid)

		SERPINB5	TKT
Description		serpin family B member 5	transketolase
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GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Nucleoplasm Peroxisome Endoplasmic Reticulum Membrane Cytosol Nuclear Body Vesicle Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Magnesium Ion Binding Transketolase Activity Calcium Ion Binding Protein Binding Thiamine Pyrophosphate Binding Protein Homodimerization Activity
	Biological Process	Morphogenesis Of An Epithelium Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Regulation Of Epithelial Cell Proliferation Prostate Gland Morphogenesis	Xylulose Biosynthetic Process Pentose-phosphate Shunt Pentose-phosphate Shunt, Non-oxidative Branch Regulation Of Growth Glyceraldehyde-3-phosphate Biosynthetic Process Ribose Phosphate Biosynthetic Process
Pathways			Insulin effects increased synthesis of Xylulose-5-Phosphate Pentose phosphate pathway
Drugs		S,S-(2-Hydroxyethyl)Thiocysteine	Copper
Diseases
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) (anti-microtubule) ( 24025145)	Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Body mass index ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) QRS duration ( 27577874 30012220 27659466) Refractive error ( 32231278)
Interacting Genes		26 interacting genes: AKT1 ATIC BASP1 BCAR3 CASP8 COL1A2 EEF1A1 ESR1 GOLGA4 GSTO1 HDAC1 HSP90AA1 HSP90AB1 HSPA5 KRAS LRRFIP1 MDH1 MT1H PALB2 PPIF SMAD4 STK11 TBP TKT UCHL5 XRCC3	6 interacting genes: ITGB1BP2 LINC01554 MYOC SERPINB5 SQSTM1 TERF1
Entrez ID		5268	7086
HPRD ID		01111	06001
Ensembl ID		ENSG00000206075	ENSG00000163931
Uniprot IDs		A0A024R2B6 P36952	A0A0B4J1R6 P29401 V9HWD9
PDB IDs		1WZ9 1XQG 1XQJ 1XU8	3MOS 3OOY 4KXU 4KXV 4KXW 4KXX 4KXY 6HA3 6HAD 6RJB
Enriched GO Terms of Interacting Partners?
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