GSTO1 and RBM48

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GSTO1	RBM48
Description		glutathione S-transferase omega 1	RNA binding motif protein 48
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Extracellular Exosome	Nucleoplasm
	Molecular Function	Glutathione Transferase Activity Protein Binding Oxidoreductase Activity Glutathione Dehydrogenase (ascorbate) Activity Methylarsonate Reductase Activity	RNA Binding Protein Binding
	Biological Process	Glutathione Metabolic Process Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion L-ascorbic Acid Metabolic Process Methylation Interleukin-12-mediated Signaling Pathway Xenobiotic Catabolic Process Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Response To Arsenic-containing Substance Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process
Pathways		Methylation Glutathione conjugation Vitamin C (ascorbate) metabolism Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Glutathione
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483)	Idiopathic dilated cardiomyopathy ( 29495422)
Interacting Genes		8 interacting genes: APP CEP126 EEF1G HSPB1 KAT5 RBM48 SERPINB5 SETDB1	73 interacting genes: AMOT ANXA7 APLP1 ARMC7 ATPAF2 BID BTBD2 C11orf49 CCDC106 CCDC57 CDK5RAP2 CDKN1A CDKN2C COX17 COX5B EIF1AD ERH FAM118B FAM90A1 FXYD6 GADD45G GLYAT GSE1 GSTO1 GYS1 HSF2BP HSPB1 HSPB3 ID2 JMY KIF9 KPNA2 MAFG MAP7D1 MLH1 MLLT3 MNAT1 MPHOSPH6 NTAQ1 NUDT21 OSGEP PAFAH1B3 PCDHA4 PIBF1 PNP POLR1C PPP1R8 PRG2 PRKAB2 PSMD11 RAB27A RAD51D RFC5 RPA2 S100Z SAT1 SCNM1 SERPINB9 SH3GL3 SMN1 SPRED2 SULT1E1 TAF9 TBC1D22B TEKT4 TK1 TNFSF10 TRDMT1 TRIB3 TSR2 VIM WDR33 ZNF24
Entrez ID		9446	84060
HPRD ID		10401	13173
Ensembl ID		ENSG00000148834	ENSG00000127993
Uniprot IDs		P78417 V9HWG9	Q5RL73
PDB IDs		1EEM 3LFL 3VLN 4IS0 4YQM 4YQU 4YQV 5UEH 5V3Q 5YVN 5YVO 6MHB 6MHC 6MHD 6PNM 6PNN 6PNO
Enriched GO Terms of Interacting Partners?
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