WBP11 and DDX17

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		WBP11	DDX17
Description		WW domain binding protein 11	DEAD-box helicase 17
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Nuclear Speck Ribonucleoprotein Complex
	Molecular Function	Single-stranded DNA Binding RNA Binding Protein Binding WW Domain Binding	Transcription Coactivator Activity RNA Binding RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity
	Biological Process	MRNA Splicing, Via Spliceosome RRNA Processing MRNA Cis Splicing, Via Spliceosome	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Epithelial To Mesenchymal Transition Regulation Of Transcription By RNA Polymerase II RRNA Processing RNA Processing MiRNA Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Gene Silencing By RNA Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus Regulation Of Skeletal Muscle Cell Differentiation
Pathways		mRNA Splicing - Major Pathway	SUMOylation of transcription cofactors
Drugs
Diseases
GWAS			Menopause (age at onset) ( 26414677) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		32 interacting genes: APBB1 ARF1 C5orf22 CD2BP2 CTNNBL1 DDX17 DDX5 FYN GIGYF2 GRB2 ITSN1 MCRS1 MORN4 NCK2 NOD2 PIK3R1 PPP1CA PPP1CB PPP1CC PQBP1 PRPF40A RBM5 RTN4IP1 RUNX1T1 SEC23A SRC TESC TRAF4 TRIP10 UBASH3A VIM WBP4	38 interacting genes: APBB1 APP BYSL CCDC187 CREBBP CSNK2A1 DDX5 DDX6 ESR1 FBL FXR2 GAS8 GRB2 HDAC1 HNRNPH1 HNRNPH3 HNRNPK LNX1 NCOA1 NCOA2 NCOA3 PIN1 PTK6 PTPRD RBM10 RBM14 RBM15 RBM4 RBM5 SF1 SF3B4 SNRNP70 SORBS3 SREK1 SUMO2 WBP11 WBP2 YWHAG
Entrez ID		51729	10521
HPRD ID		18293	10532
Ensembl ID		ENSG00000084463	ENSG00000100201
Uniprot IDs		A0A024RAW9 Q9Y2W2	Q59F66 Q92841
PDB IDs			6UV0 6UV1 6UV2 6UV3 6UV4
Enriched GO Terms of Interacting Partners?
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