DDX17 and WBP2

Data Source:
BioGRID (pull down)

		DDX17	WBP2
Description		DEAD-box helicase 17	WW domain binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Nuclear Speck Ribonucleoprotein Complex	Chromatin Nucleus Cytoplasm
	Molecular Function	Transcription Coactivator Activity RNA Binding RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Estrogen Receptor Binding Chromatin DNA Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Epithelial To Mesenchymal Transition Regulation Of Transcription By RNA Polymerase II RRNA Processing RNA Processing MiRNA Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Gene Silencing By RNA Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus Regulation Of Skeletal Muscle Cell Differentiation	Response To Progesterone Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Estrogen Establishment Of Protein Localization Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Progesterone Receptor Signaling Pathway Cellular Response To Estrogen Stimulus Positive Regulation Of Histone H3-K14 Acetylation
Pathways		SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Menopause (age at onset) ( 26414677) Resting heart rate ( 27798624) Sleep duration ( 30846698)	Adult body size ( 32376654) Platelet count ( 32888494) Red blood cell count ( 32888494) White matter hyperintensities ( 32358547)
Interacting Genes		38 interacting genes: APBB1 APP BYSL CCDC187 CREBBP CSNK2A1 DDX5 DDX6 ESR1 FBL FXR2 GAS8 GRB2 HDAC1 HNRNPH1 HNRNPH3 HNRNPK LNX1 NCOA1 NCOA2 NCOA3 PIN1 PTK6 PTPRD RBM10 RBM14 RBM15 RBM4 RBM5 SF1 SF3B4 SNRNP70 SORBS3 SREK1 SUMO2 WBP11 WBP2 YWHAG	54 interacting genes: ANAPC1 ANKRD13A ANKRD13D ARCN1 BAG3 CCT7 CLEC4G COPA COPB1 COPB2 COPE COPG1 CUEDC1 DDX17 EEF1B2 EPN2 ESR1 GRPEL1 H4C1 HOMER3 HUWE1 ITCH KRT18 KRT8 KRT9 LGALS8 MAGEA4 MAGI1 MYO6 NEDD4 NEDD4L PAX8 POLH RHBDD3 RNF168 RPS27A RPS3 SDHA SEPTIN3 SMAD5 TDP2 TOLLIP TOM1L2 UBA52 UBC UBE2D3 UBE2E3 UBE3A UBQLN1 UIMC1 WWP1 WWP2 WWTR1 YAP1
Entrez ID		10521	23558
HPRD ID		10532	06097
Ensembl ID		ENSG00000100201	ENSG00000132471
Uniprot IDs		Q59F66 Q92841	A0A024R8L1 Q969T9
PDB IDs		6UV0 6UV1 6UV2 6UV3 6UV4
Enriched GO Terms of Interacting Partners?
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