ANKFY1 and EHD1

Data Source:
BioGRID (two hybrid, pull down, two hybrid)

		ANKFY1	EHD1
Description		ankyrin repeat and FYVE domain containing 1	EH domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Cytosol Endosome Membrane Membrane Retromer Complex Intracellular Membrane-bounded Organelle Macropinosome Extracellular Exosome	Cytoplasm Early Endosome Lipid Droplet Plasma Membrane Endosome Membrane Membrane Ciliary Pocket Membrane Endocytic Vesicle Platelet Dense Tubular Network Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Small GTPase Binding Metal Ion Binding Phosphatidylinositol Phosphate Binding	Calcium Ion Binding Protein Binding ATP Binding GTP Binding Small GTPase Binding Identical Protein Binding Cadherin Binding
	Biological Process	Endocytosis Endosomal Transport Endosomal Vesicle Fusion Retrograde Transport, Endosome To Golgi Positive Regulation Of Pinocytosis Golgi To Lysosome Transport	Intracellular Protein Transport Endocytosis Blood Coagulation Positive Regulation Of Cholesterol Storage Endosomal Transport Neuron Projection Development Endocytic Recycling Low-density Lipoprotein Particle Clearance Cholesterol Homeostasis Protein Homooligomerization Cilium Assembly Protein Localization To Cilium Protein Localization To Plasma Membrane Positive Regulation Of Myoblast Fusion Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of Endocytic Recycling
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30578418) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Hematocrit ( 32888494) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: ANKRD28 CLK1 EHD1 RAB5A RHOD RHOF SRPK2	13 interacting genes: ANKFY1 AP2A1 EHBP1 EHD3 HSPB1 IGF1R MICAL1 MICALL1 MUL1 RAB11FIP2 RBSN RFFL SNAP29
Entrez ID		51479	10938
HPRD ID		09717	09325
Ensembl ID		ENSG00000185722	ENSG00000110047
Uniprot IDs		B3KPZ0 Q9P2R3	A0A024R571 B2R5U3 Q9H4M9
PDB IDs			2JQ6 2KFF 2KFG 2KFH 2KSP
Enriched GO Terms of Interacting Partners?
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