ANKFY1 and RHOF

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		ANKFY1	RHOF
Description		ankyrin repeat and FYVE domain containing 1	ras homolog family member F, filopodia associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Cytosol Endosome Membrane Membrane Retromer Complex Intracellular Membrane-bounded Organelle Macropinosome Extracellular Exosome	Cytosol Cytoskeleton Plasma Membrane Cell Cortex Secretory Granule Membrane Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding Small GTPase Binding Metal Ion Binding Phosphatidylinositol Phosphate Binding	GTPase Activity GTP Binding Protein Kinase Binding
	Biological Process	Endocytosis Endosomal Transport Endosomal Vesicle Fusion Retrograde Transport, Endosome To Golgi Positive Regulation Of Pinocytosis Golgi To Lysosome Transport	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Neutrophil Degranulation Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle Neutrophil degranulation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30578418) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Hematocrit ( 32888494) Refractive error ( 32231278)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 31194788 32888494 27863252) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		7 interacting genes: ANKRD28 CLK1 EHD1 RAB5A RHOD RHOF SRPK2	1 interacting genes: ANKFY1
Entrez ID		51479	54509
HPRD ID		09717	15246
Ensembl ID		ENSG00000185722	ENSG00000139725
Uniprot IDs		B3KPZ0 Q9P2R3	Q9HBH0
PDB IDs
Enriched GO Terms of Interacting Partners?
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