COMMD10 and SCNN1B

Data Source:
BioGRID (pull down)

		COMMD10	SCNN1B
Description		COMM domain containing 10	sodium channel epithelial 1 subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Membrane Sodium Channel Complex Extracellular Exosome Plasma Membrane Protein Complex
	Molecular Function	Protein Binding	Protein Binding Ligand-gated Sodium Channel Activity WW Domain Binding
	Biological Process		Sodium Ion Transport Excretion Gene Expression Artery Smooth Muscle Contraction Ion Transmembrane Transport Sodium Ion Transmembrane Transport Epithelial Fluid Transport Response To Drug Multicellular Organismal Water Homeostasis Sensory Perception Of Taste Sodium Ion Homeostasis Cellular Response To Aldosterone
Pathways		Neddylation	Stimuli-sensing channels
Drugs			Triamterene Amiloride
Diseases			Liddle syndrome Hyperkalemic distal renal tubular acidosis (RTA type 4), including the following two diseases: Pseudohypoaldosteronism type I (PHA1); Pseudohypoaldosteronism type II (Gordon's syndrome) Bronchiectasis with or without elevated sweat chloride
GWAS		Ankle-brachial index ( 31388106) Asthma or chronic obstructive pulmonary disease ( 24993907) Bipolar disorder and schizophrenia ( 22688191) Inflammatory biomarkers ( 22228203) Metabolite levels (X-11787) ( 23934736)	Kidney stones ( 31729369)
Interacting Genes		5 interacting genes: COMMD1 COMMD5 SCNN1A SCNN1B SCNN1G	14 interacting genes: ANK3 CNTN1 COMMD10 EPN1 HECW1 ITCH NEDD4 NEDD4L NFASC SCNN1A SCNN1D SCNN1G STX1A WWP2
Entrez ID		51397	6338
HPRD ID		16734	02861
Ensembl ID		ENSG00000145781	ENSG00000168447
Uniprot IDs		D6RJ90 Q9Y6G5	B2R812 P51168
PDB IDs			6BQN 6WTH
Enriched GO Terms of Interacting Partners?
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