CEP19 and EVI5

Data Source:
BioGRID (two hybrid)

		CEP19	EVI5
Description		centrosomal protein 19	ecotropic viral integration site 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Centriole Cilium Ciliary Basal Body	Nucleus Microtubule Organizing Center Spindle Cytosol
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Microtubule Anchoring At Centrosome Cilium Assembly Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment	Intracellular Protein Transport Cell Cycle Retrograde Transport, Endosome To Golgi Positive Regulation Of GTPase Activity Cell Division Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 31959851 30929738)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Apolipoprotein B levels ( 32203549) Asthma or allergic disease (pleiotropy) ( 29785011) Cholesterol, total ( 24097068 25961943 20686565) Epstein Barr virus nuclear antigen 1 IgG levels or multiple sclerosis ( 26819262) LDL cholesterol ( 30275531 25961943) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244 24076602 19525955 21833088 27386562) Systemic lupus erythematosus ( 28714469) Total cholesterol levels ( 28334899 30275531)
Interacting Genes		50 interacting genes: AK4 ANAPC15 C4orf19 CALCOCO1 CCDC102B CCDC106 CCDC74A CDR1 CEP350 CEP43 CREB3L2 CREB3L3 EVI5 FOXR1 GMEB2 GNL3 HSPB2 HSPB2-C11orf52 KIAA1958 KXD1 LYSMD2 NOTO PAPSS2 PEX13 PIBF1 PICK1 PIK3R3 PLEKHO1 PRAP1 PRKAR1B PTPN23 RABL2A RABL2B REL ROBO4 SENP3 SYNE4 TNNI1 TRAIP TSPYL2 TVP23B TXLNB VCP VPS52 ZBTB10 ZBTB14 ZFP1 ZNF420 ZNF438 ZNF81	22 interacting genes: ARL4A AURKB BIRC5 CCDC185 CEP19 CSNK1D ELOA FAM161A FBXO5 IMP3 INCENP LENG1 LMO1 MB21D2 MCRS1 MORF4L2 PRPF31 REP15 STX3 TCEANC TNFAIP8L1 ZNF446
Entrez ID		84984	7813
HPRD ID		17488	04249
Ensembl ID		ENSG00000174007	ENSG00000067208
Uniprot IDs		Q96LK0	O60447 Q59FE7
PDB IDs
Enriched GO Terms of Interacting Partners?
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