PCMT1 and CLP1

Data Source:
BioGRID (two hybrid)

		PCMT1	CLP1
Description		protein-L-isoaspartate (D-aspartate) O-methyltransferase	cleavage factor polyribonucleotide kinase subunit 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome Extracellular Vesicle	TRNA-intron Endonuclease Complex Nucleus Nucleoplasm Cytosol MRNA Cleavage Factor Complex
	Molecular Function	Protein-L-isoaspartate (D-aspartate) O-methyltransferase Activity Protein Binding Cadherin Binding	Protein Binding ATP Binding ATP-dependent Polydeoxyribonucleotide 5'-hydroxyl-kinase Activity Polynucleotide 5'-hydroxyl-kinase Activity Polydeoxyribonucleotide Kinase Activity ATP-dependent Polyribonucleotide 5'-hydroxyl-kinase Activity
	Biological Process	Protein Methylation Protein Repair	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation RNA Processing Phosphorylation Cerebellar Cortex Development Targeting Of MRNA For Destruction Involved In RNA Interference MRNA 3'-end Processing SiRNA Loading Onto RISC Involved In RNA Interference
Pathways		Protein repair	tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs		S-adenosyl-L-homocysteine
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Autism spectrum disorder or schizophrenia ( 28540026) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Neuroticism ( 29255261) Schizophrenia ( 25056061 29483656)
Interacting Genes		12 interacting genes: AGTR1 APOA1 APOE CCR2 CHD3 CLP1 CREBBP CYSLTR2 IQCB1 RPIA TAAR1 VKORC1	17 interacting genes: APP CCDC130 CEP164 CPSF3 CREB3 DAGLB FGF16 FTO HCFC1 MEOX2 MESD NUDT21 PCMT1 PRR3 PSMB5 SNF8 TSEN54
Entrez ID		5110	10978
HPRD ID		08908	16382
Ensembl ID		ENSG00000120265	ENSG00000172409
Uniprot IDs		A0A0A0MRJ6 A0A3F2YNX8 B7Z972 F6S8N6 P22061	Q92989
PDB IDs		1I1N 1KR5
Enriched GO Terms of Interacting Partners?
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