CLP1 and CCDC130

Data Source:
BioGRID (two hybrid)

		CLP1	CCDC130
Description		cleavage factor polyribonucleotide kinase subunit 1	coiled-coil domain containing 130
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	TRNA-intron Endonuclease Complex Nucleus Nucleoplasm Cytosol MRNA Cleavage Factor Complex	Cellular_component U2-type Spliceosomal Complex Post-mRNA Release Spliceosomal Complex
	Molecular Function	Protein Binding ATP Binding ATP-dependent Polydeoxyribonucleotide 5'-hydroxyl-kinase Activity Polynucleotide 5'-hydroxyl-kinase Activity Polydeoxyribonucleotide Kinase Activity ATP-dependent Polyribonucleotide 5'-hydroxyl-kinase Activity	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation RNA Processing Phosphorylation Cerebellar Cortex Development Targeting Of MRNA For Destruction Involved In RNA Interference MRNA 3'-end Processing SiRNA Loading Onto RISC Involved In RNA Interference	RNA Splicing Response To Virus
Pathways		tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Neuroticism ( 29255261) Schizophrenia ( 25056061 29483656)
Interacting Genes		17 interacting genes: APP CCDC130 CEP164 CPSF3 CREB3 DAGLB FGF16 FTO HCFC1 MEOX2 MESD NUDT21 PCMT1 PRR3 PSMB5 SNF8 TSEN54	26 interacting genes: CLP1 EEF1A1 EFHC1 HSF2BP JUP NINL SMARCD1 TRAF2 TRIM55 TRIM63 TSSK3 ZBTB16 ZFP3 ZNF165 ZNF17 ZNF24 ZNF250 ZNF3 ZNF329 ZNF35 ZNF572 ZNF629 ZNF774 ZNF79 ZNF835 ZSCAN23
Entrez ID		10978	81576
HPRD ID		16382	11304
Ensembl ID		ENSG00000172409	ENSG00000104957
Uniprot IDs		Q92989	B7Z1U2 P13994
PDB IDs
Enriched GO Terms of Interacting Partners?
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