CTSA and LTB4R2

Data Source:
BioGRID (two hybrid)

		CTSA	LTB4R2
Description		cathepsin A	leukotriene B4 receptor 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Lysosome Endoplasmic Reticulum Membrane Azurophil Granule Lumen Lysosomal Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Lumenal Side Of Lysosomal Membrane	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Carboxypeptidase Activity Serine-type Carboxypeptidase Activity Enzyme Activator Activity	Leukotriene B4 Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Proteolysis Glycosphingolipid Metabolic Process Intracellular Protein Transport Regulation Of Protein Stability Neutrophil Degranulation Regulation Of Catalytic Activity Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Chaperone-mediated Autophagy	Chemotaxis Inflammatory Response G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Signaling Pathway Leukotriene Signaling Pathway
Pathways		Glycosphingolipid metabolism MHC class II antigen presentation Sialic acid metabolism Defective NEU1 causes sialidosis Neutrophil degranulation	Leukotriene receptors G alpha (q) signalling events
Drugs			Amelubant Leukotriene B4
Diseases		Galactosialidosis
GWAS			Anorectal malformation ( 31136621) Height ( 28552196)
Interacting Genes		45 interacting genes: AHNAK2 AQP2 AQP6 ARL13B ASPH BSND CD79A COQ9 CPLX4 CREB3L1 CSPG5 ERGIC3 FAM209A FKBP7 FNDC9 GLB1 GORAB HIBADH LAMP2 LMNA LTB4R2 MFSD14B MGST3 MUC1 MYG1 NEU1 PSCA REEP4 RHBDD1 RNF122 SAR1A SGMS2 SIGLEC12 SLC18A1 SLC30A2 SPN SSMEM1 STX2 THAP4 TMEM139 TMEM154 TMEM237 TMEM31 TMEM35A TMX2	46 interacting genes: AKT1 AP2M1 CANX CEBPZ CERS1 CHPT1 CNOT10 CRELD2 CSNK2B CTSA DDOST FOLR1 GJC2 GLOD4 GPR146 GPR37 HLA-A IL17RD IMP4 LAMP5 MDH1 MGLL MYO1E OBSL1 P4HTM PER1 PIGM PKD1 RPN2 SCARB1 SEC13 SGCB SLC2A1 STMN3 SV2A SYNGR2 TMED1 TMEM94 TMUB2 TSPAN3 TSPAN4 TSPAN7 TTC9B VPS25 WFS1 YIF1B
Entrez ID		5476	56413
HPRD ID		02020	16153
Ensembl ID		ENSG00000064601	ENSG00000213906
Uniprot IDs		B4E324 P10619 X6R5C5 X6R8A1	B4E292 Q9NPC1
PDB IDs		1IVY 3BP4 3BP7 3BXN 4AZ0 4AZ3 4CI9 4CIA 4CIB 4MWS 4MWT 6WIA
Enriched GO Terms of Interacting Partners?
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