PBX3 and PLIN3

Data Source:
BioGRID (two hybrid)

		PBX3	PLIN3
Description		PBX homeobox 3	perilipin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytoplasm Endosome Golgi Apparatus Lipid Droplet Cytosol Endosome Membrane Membrane Transport Vesicle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific	Protein Binding Cadherin Binding
	Biological Process	Eye Development Regulation Of Transcription By RNA Polymerase II Anterior Compartment Pattern Formation Posterior Compartment Specification Brain Development Animal Organ Morphogenesis Embryonic Organ Development Neuron Development	Positive Regulation Of Sequestering Of Triglyceride Vesicle-mediated Transport Lipid Storage
Pathways			Triglyceride catabolism Retrograde transport at the Trans-Golgi-Network Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy RHOBTB3 ATPase cycle
Drugs			Idursulfase Galsulfase
Diseases
GWAS		Dentures ( 31235808) Fish- and plant-related diet ( 32066663) Medication use (opioids) ( 31015401) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Pulse pressure ( 30578418) Raw vegetable consumption ( 32066663) Refractive error ( 32231278) Response to mTOR inhibitor (everolimus) ( 24009623) Sleep duration ( 30531941) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418)	Basal cell carcinoma ( 27539887) Lung cancer in ever smokers ( 28604730) Visceral fat ( 30942860)
Interacting Genes		63 interacting genes: AGTRAP ARFIP2 ARL6IP1 BIK BSND CAV3 CIDEB CMTM4 CMTM5 COQ8A CPLX2 DESI2 DGAT2L6 FADS6 FAM177A1 FKBP7 FSD2 GAD2 GBP7 HIGD1C HOXA9 HOXB8 HSD17B13 INPP5K INSYN1 ITGB3BP KRT27 KRT31 LIME1 MAGEA1 MAGEC2 MAL2 MBLAC2 MDK MEIS1 MICOS13 MTERF3 NUDT9 PLIN3 PRB3 PTPN9 RABAC1 REEP5 RHBDD2 RHEX RNF186 RPRM SCAMP1 SFT2D2 SIN3A SMPD2 SYP SYPL1 TFIP11 TMCO2 TMEM196 TPD52L1 TPM3 TRAF1 TRIM44 TVP23B ZNF655 ZNHIT3	32 interacting genes: ABHD4 ABHD5 APP CCNC CHMP4B CMTM5 CPD CYBC1 GAD2 HSD17B13 IGF2R LNPK M6PR MAX MIEF1 MYG1 PBX3 PIAS3 PTPN9 RAB9A SFT2D2 SMAD2 SNX1 SNX2 SPART SYNGR1 SYNGR3 SYP TARS2 TBC1D13 TBPL1 TMEM14C
Entrez ID		5090	10226
HPRD ID		15938	04080
Ensembl ID		ENSG00000167081	ENSG00000105355
Uniprot IDs		P40426 Q5JS98 Q96AL5	A0A140VJN8 O60664
PDB IDs
Enriched GO Terms of Interacting Partners?
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