PBX3 and MAGEA1

Data Source:
BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology)

		PBX3	MAGEA1
Description		PBX homeobox 3	MAGE family member A1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific	Protein Binding Histone Deacetylase Binding
	Biological Process	Eye Development Regulation Of Transcription By RNA Polymerase II Anterior Compartment Pattern Formation Posterior Compartment Specification Brain Development Animal Organ Morphogenesis Embryonic Organ Development Neuron Development	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Notch Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Dentures ( 31235808) Fish- and plant-related diet ( 32066663) Medication use (opioids) ( 31015401) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Pulse pressure ( 30578418) Raw vegetable consumption ( 32066663) Refractive error ( 32231278) Response to mTOR inhibitor (everolimus) ( 24009623) Sleep duration ( 30531941) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418)
Interacting Genes		63 interacting genes: AGTRAP ARFIP2 ARL6IP1 BIK BSND CAV3 CIDEB CMTM4 CMTM5 COQ8A CPLX2 DESI2 DGAT2L6 FADS6 FAM177A1 FKBP7 FSD2 GAD2 GBP7 HIGD1C HOXA9 HOXB8 HSD17B13 INPP5K INSYN1 ITGB3BP KRT27 KRT31 LIME1 MAGEA1 MAGEC2 MAL2 MBLAC2 MDK MEIS1 MICOS13 MTERF3 NUDT9 PLIN3 PRB3 PTPN9 RABAC1 REEP5 RHBDD2 RHEX RNF186 RPRM SCAMP1 SFT2D2 SIN3A SMPD2 SYP SYPL1 TFIP11 TMCO2 TMEM196 TPD52L1 TPM3 TRAF1 TRIM44 TVP23B ZNF655 ZNHIT3	25 interacting genes: ABI2 CEP57L1 DNM1L HDAC1 HLA-A HLA-B HYPK LRSAM1 MDM4 MIEF1 NOTCH1 PBX3 PCGF6 RAB17 RNF166 S100A9 SELPLG SFN SGK1 SH3GLB2 SHFL SNW1 TRIM31 UQCRB ZNF564
Entrez ID		5090	4100
HPRD ID		15938	02059
Ensembl ID		ENSG00000167081	ENSG00000198681
Uniprot IDs		P40426 Q5JS98 Q96AL5	P43355
PDB IDs			1W72 3BO8
Enriched GO Terms of Interacting Partners?
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