MATR3 and TNFRSF21

Data Source:
BioGRID (two hybrid)

		MATR3	TNFRSF21
Description		matrin 3	TNF receptor superfamily member 21
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Membrane Nuclear Matrix	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Axon Intrinsic Component Of Plasma Membrane
	Molecular Function	RNA Binding Structural Molecule Activity Protein Binding Zinc Ion Binding MiRNA Binding Identical Protein Binding	Protein Binding
	Biological Process	Activation Of Innate Immune Response Heart Valve Development Ventricular Septum Development Posttranscriptional Regulation Of Gene Expression Innate Immune Response	B Cell Apoptotic Process Adaptive Immune Response Apoptotic Process Humoral Immune Response Axonal Fasciculation Viral Process Regulation Of Lipid Metabolic Process Negative Regulation Of B Cell Proliferation Negative Regulation Of Myelination Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-5 Production Negative Regulation Of T Cell Proliferation Myelination Regulation Of Oligodendrocyte Differentiation T Cell Receptor Signaling Pathway Neuron Apoptotic Process Cellular Response To Tumor Necrosis Factor Oligodendrocyte Apoptotic Process
Pathways			PPARA activates gene expression
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
GWAS		Body mass index ( 26426971) Malaria ( 31844061) Metabolite levels ( 23823483)	Panic disorder ( 19165232) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122)
Interacting Genes		99 interacting genes: AIMP2 AKTIP CALM1 CDC42 EGFR ERG GFI1B HNRNPK HTR2B KRT27 KRT34 LMNA MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PCBP1 PCBP3 PLEKHG4 PTBP2 PTEN RASD1 SNAP23 SNRNP200 SRPK2 TNFRSF21 TRAF1 TRAF6 TSGA10 TTF2 UBE2I	7 interacting genes: CLIP3 MATR3 NSD1 SGTA STX11 TRADD WASH2P
Entrez ID		9782	27242
HPRD ID		05270	05759
Ensembl ID		ENSG00000015479	ENSG00000146072
Uniprot IDs		A0A0R4J2E8 B3KM87 B4DF66 P43243 Q9H4N1	A0A024RD71 O75509
PDB IDs			2DBH 3QO4 3U3P 3U3Q 3U3S 3U3T 3U3V
Enriched GO Terms of Interacting Partners?
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