QKI and CARM1

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		QKI	CARM1
Description		QKI, KH domain containing RNA binding	coactivator associated arginine methyltransferase 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Synapse	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Binding MRNA Binding Protein Binding SH3 Domain Binding	Transcription Regulatory Region Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein Methyltransferase Activity Histone-arginine N-methyltransferase Activity Protein-arginine N-methyltransferase Activity Nuclear Receptor Coactivator Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity (H3-R17 Specific) Histone Methyltransferase Activity Lysine-acetylated Histone Binding
	Biological Process	Vasculogenesis MRNA Processing Regulation Of Translation Spermatid Development RNA Splicing Positive Regulation Of Gene Expression Myelination Muscle Cell Differentiation Long-chain Fatty Acid Biosynthetic Process Regulation Of MRNA Splicing, Via Spliceosome MRNA Transport	Regulation Of Transcription, DNA-templated DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Aging Positive Regulation Of Cell Population Proliferation Viral Process Histone Methylation Regulation Of Lipid Metabolic Process Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Regulation Of Intracellular Estrogen Receptor Signaling Pathway Histone H3-R2 Methylation Histone H3-R17 Methylation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Response To CAMP Regulation Of MRNA Binding Negative Regulation Of Dendrite Development
Pathways		Signaling by BRAF and RAF fusions	RORA activates gene expression BMAL1:CLOCK,NPAS2 activates circadian gene expression PPARA activates gene expression PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Activation of gene expression by SREBF (SREBP) RMTs methylate histone arginines Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by PPARalpha Circadian Clock TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Diisocyanate-induced asthma ( 25918132) Height ( 31562340) Hemoglobin ( 32888494) Incident myocardial infarction ( 26950853) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Platelet distribution width ( 32888494) Red blood cell count ( 29403010) Refractive error ( 32231278) Response to TNF antagonist treatment ( 18615156) Seasonality and depression ( 30217971) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969 30718926)	C-reactive protein levels or LDL-cholesterol levels (pleiotropy) ( 27286809) C-reactive protein levels or total cholesterol levels (pleiotropy) ( 27286809) Psoriasis ( 25574825 23143594) Psoriasis vulgaris ( 26626624)
Interacting Genes		50 interacting genes: APP ATXN1 CARM1 CCND3 CDKN2D DAZ1 DAZ4 DEPP1 DMRTB1 FBXO7 FHL3 FUBP3 HCLS1 HNRNPH2 HNRNPK IL7R LSM3 MIR141 MIR19B2 MIR200A MIR34B MIR34C MIR7-1 NABP1 PCBP1 PCBP2 PCBP4 PIAS1 PRKAB2 PRMT1 PSMF1 PTBP1 PTBP2 RALY RBFOX1 RBFOX2 RBM11 RBM14 RBM23 RBPMS RNF138 SERF2 SNRPA TEX11 THAP1 TIAL1 TSG101 U2AF2 USH1C WDR77	33 interacting genes: AXIN1 CREBBP CTNNB1 DAXX DNAJA3 DZIP3 ELAVL1 EP300 FLII FOS GRIP1 H3-3A H3-3B H3C1 MALT1 MEF2D MYOD1 MYOG NCOA1 NCOA2 NUDT21 PABPC1 PABPN1 PRMT8 PYGO1 QKI RABGAP1 RELA SMARCA4 SPAG8 SRCAP TP53 UBE2I
Entrez ID		9444	10498
HPRD ID		06691	09158
Ensembl ID		ENSG00000112531	ENSG00000142453
Uniprot IDs		Q8WY44 Q96PU8	Q86X55
PDB IDs		4JVH	2Y1W 2Y1X 4IKP 5DWQ 5DX0 5DX1 5DX8 5DXA 5DXJ 5U4X 6ARJ 6ARV 6D2L 6DVR 6IZQ 6S70 6S71 6S74 6S77 6S79 6S7A 6S7B 6S7C
Enriched GO Terms of Interacting Partners?
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