SPAG4 and TMEM187

Data Source:
BioGRID (two hybrid)

		SPAG4	TMEM187
Description		sperm associated antigen 4	transmembrane protein 187
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Cytoplasm Cytoskeleton Integral Component Of Membrane Motile Cilium Meiotic Nuclear Membrane Microtubule Tethering Complex	Integral Component Of Membrane Transport Vesicle
	Molecular Function	Structural Molecule Activity Protein Binding Protein-membrane Adaptor Activity	Molecular_function Protein Binding
	Biological Process	Nuclear Envelope Organization Spermatogenesis Cell Differentiation	Biological_process
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Celiac disease ( 22057235) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus ( 26663301 26502338)
Interacting Genes		24 interacting genes: ABHD16A ASGR1 BMP10 CSGALNACT1 ERMP1 GOSR2 IGFBP5 MS4A13 NRM ODF1 PAXIP1 PGA4 PLN PTPN9 RUSF1 SCAMP4 SCD SEC22A SUN5 TMEM187 TMEM60 TNMD TRARG1 TSPO2	15 interacting genes: ADRB2 ARL13B CD79A CGRRF1 CISD2 COMT FAM210B GORAB LEUTX MUC1 PGRMC2 SAR1A SPAG4 TAS2R5 TMEM14B
Entrez ID		6676	8269
HPRD ID		04330	02086
Ensembl ID		ENSG00000061656	ENSG00000177854
Uniprot IDs		Q9NPE6	Q14656
PDB IDs
Enriched GO Terms of Interacting Partners?
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