RAMP1 and MAL

Data Source:
BioGRID (two hybrid)

		RAMP1	MAL
Description		receptor activity modifying protein 1	mal, T cell differentiation protein
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex Amylin Receptor Complex 1 CGRP Receptor Complex	Endoplasmic Reticulum Integral Component Of Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Membrane Raft
	Molecular Function	Calcitonin Gene-related Peptide Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity Calcitonin Gene-related Peptide Binding	Protein Binding Lipid Binding Peptidase Activator Activity Involved In Apoptotic Process Structural Constituent Of Myelin Sheath
	Biological Process	Angiogenesis Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Transport Receptor Internalization Positive Regulation Of Protein Binding Cellular Response To Hormone Stimulus Positive Regulation Of Protein Glycosylation Protein Localization To Plasma Membrane Amylin Receptor Signaling Pathway Calcitonin Gene-related Peptide Receptor Signaling Pathway	Membrane Raft Polarization Apoptotic Process Central Nervous System Development Cell Differentiation Myelination Apical Protein Localization
Pathways		G alpha (s) signalling events Calcitonin-like ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs		Pramlintide
Diseases
GWAS		Obesity-related traits ( 23251661) Resting metabolic rate ( 28476931)
Interacting Genes		9 interacting genes: CALCA CALCR CALCRL IAPP MAL MS4A13 NKG7 SLC31A2 VIPR1	81 interacting genes: AMHR2 AQP6 BCL2L13 BTN2A1 CALN1 CD300LG CD3G CD40 CD53 CD69 CLDN14 CLDN20 CLDN7 CLDN9 CLEC4C CLSTN3 CPLX4 CREB3L1 CXADR DAGLA EDA EMP1 EVI2A FAM209A FCRL2 FIBCD1 FNDC9 GJA8 GJB1 GPR152 GRAMD1A GSG1L HIBADH IL10RA IL20RB JAML KCNA1 KCNA10 KCNMB4 KLRC1 LDLRAD1 LMAN2L LMNA LRRC25 LRTM1 LSMEM1 MC4R MS4A4A MYD88 NCAPH2 NKAIN4 NPDC1 OPRM1 PERP PLA2G10 PRRT1 PTPRN RAMP1 SDC4 SGCB SHISA3 SHISA4 SLC10A1 SLC35C2 SMIM3 SPINT1 STX1A SYNDIG1 TEX29 TIGIT TM4SF18 TMEM106C TMEM174 TMEM207 TMEM213 TMEM248 TMEM30A TMEM52B TNFSF14 TSPO2 USP7
Entrez ID		10267	4118
HPRD ID		05515	01789
Ensembl ID		ENSG00000132329	ENSG00000172005
Uniprot IDs		E9PC20 O60894	A0A024RE19 P21145
PDB IDs		2YX8 3N7P 3N7R 3N7S 4RWG 5V6Y 6D1U 6E3Y 6UMG 6ZHO 6ZIS
Enriched GO Terms of Interacting Partners?
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