ALDH7A1 and RECQL5

Data Source:
HPRD (two hybrid)

		ALDH7A1	RECQL5
Description		aldehyde dehydrogenase 7 family member A1	RecQ like helicase 5
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Extracellular Exosome	Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol RNA Polymerase II, Holoenzyme
	Molecular Function	Aldehyde Dehydrogenase (NAD+) Activity L-aminoadipate-semialdehyde Dehydrogenase Activity Protein Binding Betaine-aldehyde Dehydrogenase Activity Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (non-phosphorylating) Activity	RNA Polymerase II Complex Binding Nucleic Acid Binding DNA Helicase Activity ATP Binding Four-way Junction Helicase Activity 3'-5' DNA Helicase Activity
	Biological Process	Cellular Aldehyde Metabolic Process Lysine Catabolic Process Sensory Perception Of Sound Glycine Betaine Biosynthetic Process From Choline Choline Catabolic Process	Mitotic Cell Cycle Double-strand Break Repair Via Homologous Recombination DNA Metabolic Process DNA Replication DNA Unwinding Involved In DNA Replication DNA Repair DNA Recombination DNA Duplex Unwinding Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Cellular Response To Drug Cell Division Chromosome Separation Cellular Response To Camptothecin Replication-born Double-strand Break Repair Via Sister Chromatid Exchange Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways		Choline catabolism Lysine catabolism
Drugs		NADH Artenimol
Diseases
GWAS		Colorectal cancer ( 30529582) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Metabolite levels ( 23823483) Osteoporosis ( 20072603)	Deep white matter hyperintensities ( 32517579) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Periventricular white matter hyperintensities ( 32517579)
Interacting Genes		5 interacting genes: APP EPS8 LCN2 MYG1 RECQL5	20 interacting genes: ADCY10P1 ALDH7A1 BNIPL CREB1 CUX1 DDX42 EEF1G ITGB3BP MAPK8IP1 MRE11 MTSS1 MUS81 NBN PLK1 RAD50 RAD51 STAMBP TIMP1 TOP3A TOP3B
Entrez ID		501	9400
HPRD ID		00124	04806
Ensembl ID		ENSG00000164904	ENSG00000108469
Uniprot IDs		P49419	A0A024R8M9 A0A024R8S8 B3KQK2 O94762 Q8WYH5
PDB IDs		2J6L 4X0T 4X0U 4ZUK 4ZUL 4ZVW 4ZVX 4ZVY 6O4B 6O4C 6O4D 6O4E 6O4F 6O4G 6O4H 6O4I 6O4K 6O4L 6U2X	4BK0 5LB3 5LB5 5LB8 5LBA
Enriched GO Terms of Interacting Partners?
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