RECQL5 and CUX1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RECQL5	CUX1
Description		RecQ like helicase 5	cut like homeobox 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol RNA Polymerase II, Holoenzyme	Golgi Membrane Chromatin Nucleus Nucleoplasm Golgi Apparatus Cytosol
	Molecular Function	RNA Polymerase II Complex Binding Nucleic Acid Binding DNA Helicase Activity ATP Binding Four-way Junction Helicase Activity 3'-5' DNA Helicase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein-macromolecule Adaptor Activity Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Mitotic Cell Cycle Double-strand Break Repair Via Homologous Recombination DNA Metabolic Process DNA Replication DNA Unwinding Involved In DNA Replication DNA Repair DNA Recombination DNA Duplex Unwinding Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Cellular Response To Drug Cell Division Chromosome Separation Cellular Response To Camptothecin Replication-born Double-strand Break Repair Via Sister Chromatid Exchange Negative Regulation Of Double-strand Break Repair Via Homologous Recombination	Negative Regulation Of Transcription By RNA Polymerase II Retrograde Transport, Vesicle Recycling Within Golgi Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Positive Regulation Of Dendrite Morphogenesis
Pathways			Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Intra-Golgi traffic
Drugs
Diseases
GWAS		Deep white matter hyperintensities ( 32517579) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Periventricular white matter hyperintensities ( 32517579)	Attention deficit hyperactivity disorder symptom score ( 27663945) Basal cell carcinoma ( 31174203 27539887) Breast cancer ( 29059683) Cerebellum cortex volume ( 31530798) Chronotype ( 30696823) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intelligence (MTAG) ( 29326435) Keratinocyte cancer (MTAG) ( 31174203) Mean platelet volume ( 32888494 27863252) Morning person ( 30696823) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Response to antidepressants ( 22584459) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		20 interacting genes: ADCY10P1 ALDH7A1 BNIPL CREB1 CUX1 DDX42 EEF1G ITGB3BP MAPK8IP1 MRE11 MTSS1 MUS81 NBN PLK1 RAD50 RAD51 STAMBP TIMP1 TOP3A TOP3B	21 interacting genes: BIN1 CA12 CCNA1 CDC25A CDK1 CDK7 CREBBP CTSL CYTH2 EHMT2 ELAC2 GOLGA5 HMGB1 KAT2B MAX RB1 RECQL5 SATB1 SDC3 SUMO2 TLE4
Entrez ID		9400	1523
HPRD ID		04806	00295
Ensembl ID		ENSG00000108469	ENSG00000257923
Uniprot IDs		A0A024R8M9 A0A024R8S8 B3KQK2 O94762 Q8WYH5	P39880 Q13948 Q3LIA3
PDB IDs		4BK0 5LB3 5LB5 5LB8 5LBA
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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