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OPRM1 and MFF
Data Source:
BioGRID
(two hybrid)
OPRM1
MFF
Description
opioid receptor mu 1
mitochondrial fission factor
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endosome
Endoplasmic Reticulum
Golgi Apparatus
Plasma Membrane
Integral Component Of Plasma Membrane
Focal Adhesion
Axon
Dendrite
Dendrite Membrane
Dendrite Cytoplasm
Sarcolemma
Neuron Projection
Perikaryon
Membrane Raft
Spine Apparatus
Integral Component Of Postsynaptic Membrane
Integral Component Of Presynaptic Membrane
Mitochondrion
Mitochondrial Outer Membrane
Peroxisome
Synaptic Vesicle
Integral Component Of Mitochondrial Outer Membrane
Integral Component Of Mitochondrial Membrane
Protein-containing Complex
Molecular Function
G-protein Alpha-subunit Binding
G Protein-coupled Receptor Activity
Beta-endorphin Receptor Activity
Voltage-gated Calcium Channel Activity
Protein Binding
Protein C-terminus Binding
Protein Domain Specific Binding
Filamin Binding
G-protein Beta-subunit Binding
Morphine Receptor Activity
Peptide Binding
Neuropeptide Binding
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Biological Process
Acute Inflammatory Response To Antigenic Stimulus
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Neuropeptide Signaling Pathway
Sensory Perception
Negative Regulation Of Cell Population Proliferation
Response To Radiation
Cytokine-mediated Signaling Pathway
Sensory Perception Of Pain
Adenylate Cyclase-inhibiting Opioid Receptor Signaling Pathway
Response To Food
Positive Regulation Of Appetite
Response To Lipopolysaccharide
Opioid Receptor Signaling Pathway
Wound Healing
Response To Cocaine
Eating Behavior
Estrous Cycle
Behavioral Response To Ethanol
Positive Regulation Of Neurogenesis
Regulation Of Sensory Perception Of Pain
Excitatory Postsynaptic Potential
Negative Regulation Of Wnt Protein Secretion
Positive Regulation Of ERK1 And ERK2 Cascade
Calcium Ion Transmembrane Transport
Response To Growth Factor
Cellular Response To Morphine
Regulation Of Cellular Response To Stress
Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Regulation Of NMDA Receptor Activity
Mitochondrial Fission
Release Of Cytochrome C From Mitochondria
Protein Targeting To Mitochondrion
Mitochondrial Fusion
Regulation Of Mitochondrion Organization
Peroxisome Fission
Mitochondrial Fragmentation Involved In Apoptotic Process
Mitochondrion Morphogenesis
Positive Regulation Of Mitochondrial Fission
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Positive Regulation Of Protein Targeting To Membrane
Regulation Of Peroxisome Organization
Pathways
Opioid Signalling
G-protein activation
Peptide ligand-binding receptors
G alpha (i) signalling events
Interleukin-4 and Interleukin-13 signaling
MECP2 regulates neuronal receptors and channels
Drugs
Tramadol
Morphine
Codeine
Amitriptyline
Hydromorphone
Methadone
Meperidine
Oxycodone
Levallorphan
Dextromethorphan
Butorphanol
Dextropropoxyphene
Pentazocine
Naltrexone
Sufentanil
Alfentanil
Fentanyl
Loperamide
Nalbuphine
Levorphanol
Remifentanil
Ondansetron
Anileridine
Buprenorphine
Hydrocodone
Diphenoxylate
Naloxone
Oxymorphone
Dezocine
Ketamine
Levacetylmethadol
Aripiprazole
Methadyl acetate
3-Methylthiofentanyl
Dimethylthiambutene
Diamorphine
Ethylmorphine
Etorphine
Carfentanil
Diprenorphine
Dihydromorphine
3-Methylfentanyl
V1003
Epicept NP-1
LI-301
Tapentadol
Nalmefene
Alvimopan
Morphine glucuronide
Ketobemidone
Methylnaltrexone
Naloxegol
Cannabidiol
Trimebutine
Butyrfentanyl
Pholcodine
Eluxadoline
Tianeptine
Opium
Pentoxyverine
Naldemedine
Metenkefalin
Medical Cannabis
Nabiximols
Loxicodegol
Oliceridine
Diseases
GWAS
Adult body size (
32376654
)
Body size at age 10 (
32376654
)
Diastolic blood pressure (
30224653
)
HDL cholesterol levels (
32203549
)
Hypertension (
21347282
)
Lipoprotein (a) levels (
26377243
)
Menstruation quality of life impact (fever) (
29855537
)
Methadone dose in opioid dependence (
28115739
)
Opioid use disorder (
32492095
)
Type 2 diabetes (age of onset) (
28060188
)
Intraocular pressure (
29617998
)
Refractive astigmatism (
30306274
)
Interacting Genes
77 interacting genes:
ADAM33
ADD3
ALOX5AP
ATP6V0C
ATP6V0E1
C2CD2L
CALM1
CCDC167
CD302
CLCN7
CLDN10
CLDN22
CLDN8
CLEC12B
CLEC7A
CNIH1
COPS5
CPLX1
CTXN3
CYB561
DNAJB4
DOK4
DOK5
EHHADH
EMP1
EMP3
FLNA
GJA4
GNA15
GNAI1
GNAI2
GNAO1
GPRASP1
GRK3
GRM1
HS6ST1
IFITM3
KCNF1
LAT
LPAR3
LRRC25
MAL
MALL
MAP1LC3A
MAP1LC3C
MFF
NELFA
NSG1
OPRD1
OPRL1
PLD2
PLD3
PMP22
PPL
RPRM
RTP4
SCGB1D1
SEC22A
SERP2
SIAH1
SIAH2
SLC30A2
SLC38A7
SLC39A13
SLC41A1
SLC9A9
SMAGP
TEX264
TM4SF4
TMBIM6
TMEM236
TRARG1
UBC
VAPA
WLS
YIPF3
ZYX
105 interacting genes:
ADIPOQ
AGPAT4
AIG1
ANKRD46
APOD
APOL2
AQP3
AQP6
ATP6V0B
BET1
C14orf180
C1QL4
C3orf52
CD79A
CDIPT
CEND1
CLDN19
CMTM5
CNIH1
COL4A5
CTXN3
CXCL16
CYB5B
CYBC1
DNM1L
ERGIC3
FAM209A
FAM210B
FAM3C
FATE1
FCER1G
FDCSP
FXYD6
GJB1
GKN1
GOSR2
GPR152
IGFBP5
JAGN1
LAT
LHFPL5
LPAR3
MEOX2
MIP
MMGT1
MOSPD3
MPZL1
MTNR1B
NIPAL3
NRM
NTS
OPN1SW
OPRM1
PLK3
PLLP
PLN
PLP1
RAET1L
RETREG3
RHBDL1
SACM1L
SEC11C
SEC22A
SEC22B
SEC23A
SERINC2
SHISAL1
SLC18A3
SLC35B1
SLC41A2
SLC7A1
SLC7A14
SLC7A8
SMIM1
STRIT1
STX7
STX8
TEX264
TFRC
TM6SF1
TMEM128
TMEM140
TMEM14C
TMEM201
TMEM218
TMEM229B
TMEM237
TMEM254
TMEM42
TMEM60
TMEM86B
TMEM88
TMEM97
TMX2
TRAF3IP3
TRAM1L1
TRARG1
TSPAN2
TSPAN33
TSPO2
UNC50
UNC93B1
UPK1B
VAMP4
ZFPL1
Entrez ID
4988
56947
HPRD ID
02484
16653
Ensembl ID
ENSG00000112038
ENSG00000168958
Uniprot IDs
B8K2Q5
G8XRH4
G8XRH5
L0E130
P35372
A0A0A0MS29
A1MAC2
Q9GZY8
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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