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OGG1 and CHGB
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
OGG1
CHGB
Description
8-oxoguanine DNA glycosylase
chromogranin B
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Mitochondrion
Nuclear Matrix
Nuclear Speck
Protein-containing Complex
Extracellular Space
Endoplasmic Reticulum Lumen
Secretory Granule
Molecular Function
Damaged DNA Binding
Endonuclease Activity
Protein Binding
Microtubule Binding
Oxidized Purine Nucleobase Lesion DNA N-glycosylase Activity
Oxidized Purine DNA Binding
8-oxo-7,8-dihydroguanine DNA N-glycosylase Activity
Class I DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity
Hormone Activity
Protein Binding
Biological Process
Acute Inflammatory Response
Base-excision Repair
Base-excision Repair, AP Site Formation
Regulation Of Transcription, DNA-templated
Cellular Response To DNA Damage Stimulus
Response To Oxidative Stress
Aging
Response To Radiation
Response To Light Stimulus
Response To Estradiol
Nucleotide-excision Repair, DNA Incision
Response To Drug
Negative Regulation Of Apoptotic Process
Depurination
Depyrimidination
Response To Ethanol
Response To Folic Acid
Cellular Response To Cadmium Ion
Negative Regulation Of Double-strand Break Repair Via Single-strand Annealing
Signal Transduction
Post-translational Protein Modification
Cellular Protein Metabolic Process
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Displacement of DNA glycosylase by APEX1
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway
Defective OGG1 Substrate Binding
Defective OGG1 Substrate Processing
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Drugs
Diseases
GWAS
Metabolite levels (
23823483
)
Uterine fibroid number (single vs multiple) (
30196971
)
Interacting Genes
6 interacting genes:
CHGB
HUS1
PRKCA
RAD1
RAD9A
XRCC1
34 interacting genes:
ACACA
ANXA7
APP
ATXN2
CBFB
CCDC92
CDKN1A
FGFR3
LRRK1
LRRK2
MARK3
MFHAS1
MGLL
MOGS
OGG1
PKN2
POLD1
POLR2E
PRAG1
PTEN
RAC2
RAP1B
RCC1
RXRG
S100A8
SAFB2
SLC25A6
TAZ
TK1
TUBB2A
TWF2
UBQLN1
UBTF
YLPM1
Entrez ID
4968
1114
HPRD ID
03582
07512
Ensembl ID
ENSG00000114026
ENSG00000089199
Uniprot IDs
E5KPM5
E5KPM6
E5KPM7
E5KPM8
E5KPM9
E5KPN0
E5KPN1
O15527
P05060
PDB IDs
1EBM
1FN7
1HU0
1KO9
1LWV
1LWW
1LWY
1M3H
1M3Q
1N39
1N3A
1N3C
1YQK
1YQL
1YQM
1YQR
2I5W
2NOB
2NOE
2NOF
2NOH
2NOI
2NOL
2NOZ
2XHI
3IH7
3KTU
5AN4
6RLW
6W0M
6W0R
6W13
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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