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NFKBIE and IL1A
Data Source:
HPRD
(in vitro)
NFKBIE
IL1A
Description
NFKB inhibitor epsilon
interleukin 1 alpha
Image
No pdb structure
GO Annotations
Cellular Component
Fibrillar Center
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Perinuclear Region Of Cytoplasm
Extracellular Region
Extracellular Space
Cytosol
Molecular Function
Protein Binding
Cytokine Activity
Interleukin-1 Receptor Binding
Copper Ion Binding
Protein Binding
Biological Process
D-serine Transport
Cytoplasmic Sequestering Of Transcription Factor
Fever Generation
Positive Regulation Of Cytokine Production
Connective Tissue Replacement Involved In Inflammatory Response Wound Healing
Cellular Sodium Ion Homeostasis
Apoptotic Process
Inflammatory Response
Immune Response
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Vascular Endothelial Growth Factor Production
Positive Regulation Of Gene Expression
Cytokine-mediated Signaling Pathway
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Immature T Cell Proliferation In Thymus
Cellular Response To Heat
Ectopic Germ Cell Programmed Cell Death
Positive Regulation Of Angiogenesis
Positive Regulation Of Mitotic Nuclear Division
Positive Regulation Of Transcription By RNA Polymerase II
Response To Copper Ion
Positive Regulation Of Protein Secretion
Regulation Of Nitric-oxide Synthase Activity
Positive Regulation Of Cell Division
Interleukin-1-mediated Signaling Pathway
Cellular Response To Lipopolysaccharide
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Activation of NF-kappaB in B cells
Senescence-Associated Secretory Phenotype (SASP)
Interleukin-1 processing
Interleukin-10 signaling
Interleukin-4 and Interleukin-13 signaling
Interleukin-1 signaling
Purinergic signaling in leishmaniasis infection
Drugs
Rilonacept
Diseases
Hodgkin lymphoma
Graft-versus-host disease
GWAS
Monocyte count (
27863252
)
Monocyte percentage of white cells (
32888494
27863252
)
Rheumatoid arthritis (
30423114
22446963
23028356
24390342
)
Dysmenorrheic pain severity (
29855537
)
Endometriosis (
20844546
28537267
)
Gestational age at birth (child effect) (
31477735
)
Interleukin-1-receptor antagonist levels (
22205395
)
Neutrophil count (
32888494
)
Neutrophil percentage of white cells (
32888494
)
Post-term birth (
31477735
)
Response to antipsychotic treatment in schizophrenia (working memory) (
21107309
)
Interacting Genes
15 interacting genes:
ANKHD1
C1QBP
CUL1
HDAC4
HDAC5
IL1A
JUP
KBTBD7
NCOR2
NFKB1
NFKB2
PPP6C
REL
RELA
SKP1
11 interacting genes:
CAPN1
CASP1
HAX1
IL1R1
IL1R2
IL1RAP
KPNA6
MEOX2
NDN
NFKBIE
S100A13
Entrez ID
4794
3552
HPRD ID
05181
00988
Ensembl ID
ENSG00000146232
ENSG00000115008
Uniprot IDs
A0A024RD24
O00221
Q7LC14
Q96F31
P01583
PDB IDs
1ITA
2ILA
2KKI
2L5X
5UC6
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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