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KRTAP5-7 and SDC3
Data Source:
BioGRID
(two hybrid)
KRTAP5-7
SDC3
Description
keratin associated protein 5-7
syndecan 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytosol
Keratin Filament
Golgi Lumen
Plasma Membrane
Cell Surface
Membrane
Integral Component Of Membrane
Lysosomal Lumen
Microspike
Collagen-containing Extracellular Matrix
Molecular Function
Protein Binding
Protein Binding
Identical Protein Binding
Biological Process
Keratinization
Retinoid Metabolic Process
Glycosaminoglycan Biosynthetic Process
Glycosaminoglycan Catabolic Process
Cell Migration
Leukocyte Migration
Pathways
Keratinization
A tetrasaccharide linker sequence is required for GAG synthesis
HS-GAG biosynthesis
HS-GAG biosynthesis
HS-GAG degradation
Cell surface interactions at the vascular wall
Syndecan interactions
Syndecan interactions
Defective B4GALT7 causes EDS, progeroid type
Defective B3GAT3 causes JDSSDHD
Defective EXT2 causes exostoses 2
Defective EXT1 causes exostoses 1, TRPS2 and CHDS
Defective B3GALT6 causes EDSP2 and SEMDJL1
Retinoid metabolism and transport
Drugs
Diseases
GWAS
Loneliness (
27629369
)
Interacting Genes
61 interacting genes:
ADAMTSL3
ADAMTSL4
CARD9
CD300LG
COL8A1
CRCT1
CREB5
CRY2
CYSRT1
DMRT3
DOCK2
FAM161A
GUCD1
HHEX
HOXB9
IGFBP6
IGSF8
IL2RG
ITGB5
KPRP
KRTAP10-1
KRTAP10-10
KRTAP4-2
KRTAP4-4
KRTAP5-11
KRTAP5-2
KRTAP5-6
KRTAP9-2
LCE1A
LCE1B
LCE1E
LCE2B
LCE2C
LCE2D
LCE3A
LCE3B
LCE3D
LCE3E
LCE4A
MACO1
MAPKBP1
MRGBP
MXI1
MYOM1
PHLDA1
PTPMT1
RAMP3
SAMD11
SCARF1
SDC3
SHFL
SLC39A7
SPATA3
TRIM42
UXT
WNT11
ZNF330
ZNF440
ZNF479
ZNF587
ZNF613
32 interacting genes:
AGR2
CASK
CMTM7
COL5A1
CSK
CTTN
CUX1
EPHB4
FGF2
FYN
ITGB4
KCNJ2
KRTAP1-1
KRTAP1-3
KRTAP10-3
KRTAP2-3
KRTAP2-4
KRTAP4-2
KRTAP5-7
KRTAP5-9
KRTAP9-2
LCE3D
MDK
PLN
PTN
SLC35A1
SMIM1
TMEM14C
TMEM218
TUBA1A
TUBB
TUBB2A
Entrez ID
440050
9672
HPRD ID
17251
01719
Ensembl ID
ENSG00000244411
ENSG00000162512
Uniprot IDs
Q6L8G8
O75056
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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