KRTAP5-7 and RAMP3

Data Source:
BioGRID (two hybrid)

		KRTAP5-7	RAMP3
Description		keratin associated protein 5-7	receptor activity modifying protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Lysosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex Amylin Receptor Complex 3 Adrenomedullin Receptor Complex
	Molecular Function	Protein Binding	Amyloid-beta Binding Adrenomedullin Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity
	Biological Process	Keratinization	Angiogenesis Positive Regulation Of Receptor Recycling Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Positive Regulation Of Protein Kinase A Signaling Positive Regulation Of Cell Death Protein Transport Receptor Internalization Cellular Response To Hormone Stimulus Positive Regulation Of Peptidyl-serine Phosphorylation Cross-receptor Inhibition Within G Protein-coupled Receptor Heterodimer Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Estradiol Stimulus Protein Localization To Plasma Membrane G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Amylin Receptor Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Response To Amyloid-beta Positive Regulation Of Calcium Ion Import Across Plasma Membrane Adrenomedullin Receptor Signaling Pathway
Pathways		Keratinization	G alpha (s) signalling events Calcitonin-like ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs			Pramlintide
Diseases
GWAS			Hepatic lipid content in extreme obesity ( 25246029)
Interacting Genes		61 interacting genes: ADAMTSL3 ADAMTSL4 CARD9 CD300LG COL8A1 CRCT1 CREB5 CRY2 CYSRT1 DMRT3 DOCK2 FAM161A GUCD1 HHEX HOXB9 IGFBP6 IGSF8 IL2RG ITGB5 KPRP KRTAP10-1 KRTAP10-10 KRTAP4-2 KRTAP4-4 KRTAP5-11 KRTAP5-2 KRTAP5-6 KRTAP9-2 LCE1A LCE1B LCE1E LCE2B LCE2C LCE2D LCE3A LCE3B LCE3D LCE3E LCE4A MACO1 MAPKBP1 MRGBP MXI1 MYOM1 PHLDA1 PTPMT1 RAMP3 SAMD11 SCARF1 SDC3 SHFL SLC39A7 SPATA3 TRIM42 UXT WNT11 ZNF330 ZNF440 ZNF479 ZNF587 ZNF613	15 interacting genes: CALCR CALCRL CYSRT1 HSPB3 KRTAP10-3 KRTAP5-3 KRTAP5-7 KRTAP5-9 KRTAP9-3 NBPF19 NOTCH2NLA NSF PDCD6IP SLC31A2 VIPR1
Entrez ID		440050	10268
HPRD ID		17251	05517
Ensembl ID		ENSG00000244411	ENSG00000122679
Uniprot IDs		Q6L8G8	A4D2L1 O60896
PDB IDs			6UUS 6UVA
Enriched GO Terms of Interacting Partners?
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