CRYBB2 and CRYBA1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CRYBB2	CRYBA1
Description		crystallin beta B2	crystallin beta A1
Image			No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm
	Molecular Function	Structural Molecule Activity Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding	Molecular_function Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Lens Development In Camera-type Eye Visual Perception Response To Stimulus	Negative Regulation Of Cytokine Production Lens Development In Camera-type Eye Visual Perception Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of TOR Signaling Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Anoikis
Pathways
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Mean reticulocyte volume ( 32888494) Night sleep phenotypes ( 27126917)
Interacting Genes		9 interacting genes: CRYAA CRYAB CRYBA1 CRYBA2 CRYBA4 CRYGC HSPB1 LMO4 MIP	24 interacting genes: ARID5A BANF2 CELF6 CERK CHCHD2 CRYAA CRYAB CRYBB1 CRYBB2 CRYBB3 CYSRT1 FOXH1 HOXC8 KRTAP11-1 KRTAP13-2 KRTAP13-3 LASP1 NOXA1 PLEKHF2 PROP1 RBPMS RHOXF2 VAC14 YPEL3
Entrez ID		1415	1411
HPRD ID		00430	00429
Ensembl ID		ENSG00000244752	ENSG00000108255
Uniprot IDs		P43320 R4UMM2	P05813
PDB IDs		1YTQ
Enriched GO Terms of Interacting Partners?
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