MDH1 and SERPINB5

Data Source:
BioGRID (two hybrid)

		MDH1	SERPINB5
Description		malate dehydrogenase 1	serpin family B member 5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Centrosome Cytosol Extracellular Exosome	Extracellular Space Cytoplasm
	Molecular Function	Malic Enzyme Activity Protein Binding L-malate Dehydrogenase Activity Diiodophenylpyruvate Reductase Activity	Serine-type Endopeptidase Inhibitor Activity Protein Binding
	Biological Process	Gluconeogenesis Tricarboxylic Acid Cycle Oxaloacetate Metabolic Process Malate Metabolic Process NADH Metabolic Process	Morphogenesis Of An Epithelium Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Regulation Of Epithelial Cell Proliferation Prostate Gland Morphogenesis
Pathways		Gluconeogenesis
Drugs		NADH Nicotinamide adenine dinucleotide phosphate Artenimol	S,S-(2-Hydroxyethyl)Thiocysteine
Diseases
GWAS		Asthma and attention deficit hyperactivity disorder ( 31619474) Blood protein levels ( 30072576) Smoking status (ever vs never smokers) ( 30643258)	Adverse response to chemotherapy in breast cancer (alopecia) (anti-microtubule) ( 24025145)
Interacting Genes		14 interacting genes: CDC42 CHRM2 EGFR ERBB2 FUS GPD1 HSD17B10 HSPB2 LTB4R2 MPP3 SERPINB5 TERF1 TERF2IP TP53	26 interacting genes: AKT1 ATIC BASP1 BCAR3 CASP8 COL1A2 EEF1A1 ESR1 GOLGA4 GSTO1 HDAC1 HSP90AA1 HSP90AB1 HSPA5 KRAS LRRFIP1 MDH1 MT1H PALB2 PPIF SMAD4 STK11 TBP TKT UCHL5 XRCC3
Entrez ID		4190	5268
HPRD ID		01100	01111
Ensembl ID		ENSG00000014641	ENSG00000206075
Uniprot IDs		A0A5K1VW95 P40925 V9HWF2	A0A024R2B6 P36952
PDB IDs			1WZ9 1XQG 1XQJ 1XU8
Enriched GO Terms of Interacting Partners?
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