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SMAD9 and RUBCN
Data Source:
HPRD
(two hybrid)
SMAD9
RUBCN
Description
SMAD family member 9
rubicon autophagy regulator
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
SMAD Protein Complex
Heteromeric SMAD Protein Complex
Nucleoplasm
Lysosome
Early Endosome
Late Endosome
Golgi Apparatus
Cytosol
Intracellular Membrane-bounded Organelle
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
I-SMAD Binding
Protein Binding
Phosphatidylinositol Phosphate Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Transforming Growth Factor Beta Receptor Signaling Pathway
Anatomical Structure Morphogenesis
Cell Differentiation
BMP Signaling Pathway
SMAD Protein Signal Transduction
Cellular Response To BMP Stimulus
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus
Immune System Process
Endocytosis
Phagocytosis
Autophagy
Negative Regulation Of Autophagy
Negative Regulation Of Phosphatidylinositol 3-kinase Activity
Negative Regulation Of Endocytosis
Multivesicular Body Sorting Pathway
Negative Regulation Of Autophagosome Maturation
Pathways
Signaling by BMP
Drugs
Diseases
GWAS
Coronary artery disease (
29212778
)
Heel bone mineral density (
30598549
28869591
)
Perioperative myocardial infarction in coronary artery bypass surgery (
25948407
)
Spontaneous preterm birth (preterm birth) (
25599974
)
Total body bone mineral density (
29304378
)
Interacting Genes
117 interacting genes:
ABTB1
ACTB
ACVR1
AFF1
AP2A1
ARHGAP9
ARID1B
ARNT
ASB2
ASH2L
BAZ1A
BTG2
CAMSAP1
CEP135
CHPF
CLPB
CPXM2
CSH1
CSH2
CTR9
CXXC5
CYP11A1
DIAPH3
DKK1
DNAJA3
DNAJC7
DST
DSTN
E4F1
EIF3C
EIF3E
EIF3F
ERVV-1
EVC2
EXPH5
FLI1
FN1
FTL
GRN
HEY1
HEYL
HUWE1
KDM1A
KDM6A
KMT2D
LEMD3
LMO4
LNPEP
LRP5
MACO1
MAN1A2
MAN1C1
MAN2B1
MBD1
MCM3AP
METAP1
MGAT1
MTMR10
MTMR11
NAGK
OTUB1
PABPC4
PAPPA
PELP1
PHKA2
PIR
PKP2
PLEC
PNPLA2
PPARD
PPP2R5E
PRMT6
PSAP
PSMD8
QARS1
RANBP9
RFX1
RMND5A
RNF123
RRBP1
RUBCN
SECISBP2
SF3B1
SIL1
SMAD2
SMAD3
SMAD4
SMG1
SNRNP70
SPTBN1
STAG1
SVEP1
TBCD
TERF1
TINAGL1
TOB1
TRIM29
TRIP12
TTC37
TWNK
UBA6
UBE3A
UBQLN1
UBQLN4
UNC45A
VCPIP1
VPS8
XAB2
YWHAQ
ZEB2
ZNF484
ZNF557
ZNF587
ZNF587B
ZNF592
ZNF83
ZSCAN4
15 interacting genes:
ANKRD11
BRD1
BYSL
DPF2
ENKD1
EXOC1
FAM161A
FAM9B
GAS8
NME7
SMAD9
TCEANC
VEZF1
ZNF250
ZNF648
Entrez ID
4093
9711
HPRD ID
04484
11069
Ensembl ID
ENSG00000120693
ENSG00000145016
Uniprot IDs
A0A024RDR3
O15198
Q8N4U6
Q92622
PDB IDs
6FZT
6WCW
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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