RUBCN and BYSL

Data Source:
BioGRID (two hybrid)

		RUBCN	BYSL
Description		rubicon autophagy regulator	bystin like
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GO Annotations	Cellular Component	Nucleoplasm Lysosome Early Endosome Late Endosome Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle	Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol Membrane Preribosome, Small Subunit Precursor Intracellular Membrane-bounded Organelle Apical Part Of Cell
	Molecular Function	Protein Binding Phosphatidylinositol Phosphate Binding	RNA Binding Protein Binding SnoRNA Binding
	Biological Process	Immune System Process Endocytosis Phagocytosis Autophagy Negative Regulation Of Autophagy Negative Regulation Of Phosphatidylinositol 3-kinase Activity Negative Regulation Of Endocytosis Multivesicular Body Sorting Pathway Negative Regulation Of Autophagosome Maturation	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Trophectodermal Cell Differentiation RRNA Processing Cell Population Proliferation Ribosome Biogenesis Regulation Of Protein Localization To Nucleolus
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Hematological parameters ( 19820697) Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 23263863 20139978 19862010) Menarche (age at onset) ( 27182965 25231870) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494) Red blood cell count ( 20139978)
Interacting Genes		15 interacting genes: ANKRD11 BRD1 BYSL DPF2 ENKD1 EXOC1 FAM161A FAM9B GAS8 NME7 SMAD9 TCEANC VEZF1 ZNF250 ZNF648	139 interacting genes: AIMP2 AMOTL2 APP ATP5F1B AXIN2 BEND7 BFSP1 BHLHE40 C1orf94 CAVIN4 CCDC102B CCDC136 CCDC33 CDC23 CDCA7L CEP44 CEP57L1 CEP70 COIL DDX17 DOCK8 DVL2 EAPP EMD EPS8 FAM228A FAM9B FCHO1 FXR1 FXR2 GAS8 GMCL1 GOLGA2 GOLGA6L9 GRIPAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF1 IKZF3 JRK KATNAL1 KIFC3 KLHL2 KLHL6 KRT31 KRT40 KRT8 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP4-2 L3MBTL3 LDOC1 LHX3 LMNA LMO1 LMO2 LONRF1 LTV1 LZTS1 LZTS2 MB21D2 MCIDAS MEOX1 MEOX2 MID1 MID2 MIPOL1 MKRN1 MRFAP1L1 MTUS2 NECAB2 NF2 OLIG3 OSBPL3 PDE4DIP PHC2 PICK1 PIH1D1 PNMA1 PNMA2 PRICKLE1 PSMC6 RACGAP1 RACK1 RALY RALYL RBAK RP9 RUBCN SMN1 SMN2 SNW1 SSX2IP STX11 TBC1D26 TEKT1 TFIP11 THAP1 TLE5 TNIP1 TRAF2 TRAF4 TRAK1 TRIM14 TRIM27 TRIM37 TRIM38 TRIM41 TRIM54 TRIM55 TRIP6 TRO TROAP UBE2H USH1G VIM VPS37B VPS52 WASF3 WTAP ZBTB14 ZBTB8A ZC2HC1C ZFP64 ZMAT5 ZNF212 ZNF286A ZNF426 ZNF438 ZNF48 ZNF655 ZNF668 ZNF71 ZNF835 ZRANB1 ZSCAN22
Entrez ID		9711	705
HPRD ID		11069	04848
Ensembl ID		ENSG00000145016	ENSG00000112578
Uniprot IDs		Q8N4U6 Q92622	Q13895
PDB IDs		6WCW	6G18 6G4S 6G4W
Enriched GO Terms of Interacting Partners?
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