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SMAD9 and PSAP
Data Source:
HPRD
(two hybrid)
SMAD9
PSAP
Description
SMAD family member 9
prosaposin
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
SMAD Protein Complex
Heteromeric SMAD Protein Complex
Extracellular Region
Extracellular Space
Lysosome
Lysosomal Membrane
Late Endosome
Plasma Membrane
Azurophil Granule Membrane
Lysosomal Lumen
Intracellular Membrane-bounded Organelle
Collagen-containing Extracellular Matrix
Extracellular Exosome
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
I-SMAD Binding
Protease Binding
Beta-galactosidase Activity
Protein Binding
Phospholipid Binding
Enzyme Activator Activity
Lipid Binding
Protein Homodimerization Activity
Ganglioside GM1 Binding
Ganglioside GM2 Binding
Ganglioside GM3 Binding
Ganglioside GT1b Binding
Ganglioside GP1c Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Transforming Growth Factor Beta Receptor Signaling Pathway
Anatomical Structure Morphogenesis
Cell Differentiation
BMP Signaling Pathway
SMAD Protein Signal Transduction
Cellular Response To BMP Stimulus
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus
Platelet Degranulation
Glycosphingolipid Metabolic Process
Lipid Transport
Lysosomal Transport
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Regulation Of Autophagy
Regulation Of Lipid Metabolic Process
Neutrophil Degranulation
Regulation Of Catalytic Activity
Prostate Gland Growth
Epithelial Cell Differentiation Involved In Prostate Gland Development
Ganglioside GM1 Transport To Membrane
Pathways
Signaling by BMP
Platelet degranulation
Glycosphingolipid metabolism
Peptide ligand-binding receptors
G alpha (i) signalling events
Neutrophil degranulation
Drugs
Di-Stearoyl-3-Sn-Phosphatidylethanolamine
Diseases
Krabbe disease; Globoid cell leukodystrophy
Metachromatic leukodystrophy (MLD)
Gaucher disease
GWAS
Coronary artery disease (
29212778
)
Heel bone mineral density (
30598549
28869591
)
Perioperative myocardial infarction in coronary artery bypass surgery (
25948407
)
Spontaneous preterm birth (preterm birth) (
25599974
)
Total body bone mineral density (
29304378
)
Asthma (childhood onset) (
23829686
)
Seasonality and depression (
30217971
)
Interacting Genes
117 interacting genes:
ABTB1
ACTB
ACVR1
AFF1
AP2A1
ARHGAP9
ARID1B
ARNT
ASB2
ASH2L
BAZ1A
BTG2
CAMSAP1
CEP135
CHPF
CLPB
CPXM2
CSH1
CSH2
CTR9
CXXC5
CYP11A1
DIAPH3
DKK1
DNAJA3
DNAJC7
DST
DSTN
E4F1
EIF3C
EIF3E
EIF3F
ERVV-1
EVC2
EXPH5
FLI1
FN1
FTL
GRN
HEY1
HEYL
HUWE1
KDM1A
KDM6A
KMT2D
LEMD3
LMO4
LNPEP
LRP5
MACO1
MAN1A2
MAN1C1
MAN2B1
MBD1
MCM3AP
METAP1
MGAT1
MTMR10
MTMR11
NAGK
OTUB1
PABPC4
PAPPA
PELP1
PHKA2
PIR
PKP2
PLEC
PNPLA2
PPARD
PPP2R5E
PRMT6
PSAP
PSMD8
QARS1
RANBP9
RFX1
RMND5A
RNF123
RRBP1
RUBCN
SECISBP2
SF3B1
SIL1
SMAD2
SMAD3
SMAD4
SMG1
SNRNP70
SPTBN1
STAG1
SVEP1
TBCD
TERF1
TINAGL1
TOB1
TRIM29
TRIP12
TTC37
TWNK
UBA6
UBE3A
UBQLN1
UBQLN4
UNC45A
VCPIP1
VPS8
XAB2
YWHAQ
ZEB2
ZNF484
ZNF557
ZNF587
ZNF587B
ZNF592
ZNF83
ZSCAN4
20 interacting genes:
APPBP2
BACE1
BRCA1
CD1B
CELSR1
COPS6
CPEB2
CTSD
ERBB2
GBA
MAFF
NLGN3
PEX5
PRAG1
SGCG
SMAD2
SMAD9
UBE3A
USP4
ZBED1
Entrez ID
4093
5660
HPRD ID
04484
01460
Ensembl ID
ENSG00000120693
ENSG00000197746
Uniprot IDs
A0A024RDR3
O15198
A0A024QZQ2
P07602
PDB IDs
6FZT
1M12
1N69
1SN6
2DOB
2GTG
2QYP
2R0R
2R1Q
2RB3
2Z9A
3BQP
3BQQ
4DDJ
4UEX
4V2O
6SLR
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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