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MIR29B1 and EPRS1
Data Source:
BioGRID
(unspecified method)
MIR29B1
EPRS1
Description
microRNA 29b-1
glutamyl-prolyl-tRNA synthetase 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Cytoplasm
Mitochondrion
Extracellular Exosome
Extracellular Vesicle
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Aminoacyl-tRNA Synthetase Multienzyme Complex
GAIT Complex
Ribonucleoprotein Complex
Molecular Function
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Glutamate-tRNA Ligase Activity
Proline-tRNA Ligase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
RNA Stem-loop Binding
Identical Protein Binding
Protein Homodimerization Activity
GTPase Binding
Biological Process
Negative Regulation Of Cytokine-mediated Signaling Pathway
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Triglyceride Biosynthetic Process
Positive Regulation Of Cell Migration
Negative Regulation Of Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Collagen Biosynthetic Process
Negative Regulation Of Type III Interferon Production
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Positive Regulation Of Apoptotic Process
Negative Regulation Of MAPK Cascade
Regulation Of DNA Methylation
Positive Regulation Of Fat Cell Differentiation
Negative Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Protein Secretion
Negative Regulation Of Protein Kinase B Signaling
Regulation Of Blood Vessel Remodeling
Negative Regulation Of Circulating Fibrinogen Levels
Negative Regulation Of Canonical Wnt Signaling Pathway
Cellular Response To Virus
Negative Regulation Of Interleukin-32 Production
Negative Regulation Of Extracellular Matrix Assembly
Negative Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Negative Regulation Of Amyloid-beta Formation
Negative Regulation Of Mesenchymal Stem Cell Proliferation
Negative Regulation Of Amyloid Precursor Protein Catabolic Process
Negative Regulation Of Oxidative Stress-induced Cell Death
Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Aorta Morphogenesis
Negative Regulation Of Collagen Fibril Organization
Negative Regulation Of Matrix Metallopeptidase Secretion
Positive Regulation Of Metalloendopeptidase Activity
Regulation Of Epithelium Regeneration
Negative Regulation Of Metallopeptidase Activity
Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Osteoblast Differentiation
Negative Regulation Of Intestinal Epithelial Cell Development
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
TRNA Aminoacylation For Protein Translation
Glutamyl-tRNA Aminoacylation
Prolyl-tRNA Aminoacylation
Negative Regulation Of Translation
Cellular Response To Insulin Stimulus
Protein-containing Complex Assembly
Cellular Response To Interferon-gamma
Regulation Of Long-chain Fatty Acid Import Into Cell
Pathways
Selenoamino acid metabolism
Cytosolic tRNA aminoacylation
tRNA modification in the nucleus and cytosol
Drugs
Glutamic acid
Proline
5'-O-(L-Prolylsulfamoyl)adenosine
5'-O-(L-Cysteinylsulfamoyl)adenosine
5'-O-(N-(Alanyl)sulfamoyl)adenosine
Diseases
GWAS
Pancreatic cancer (
25086665
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
72 interacting genes:
APOBEC3B
C1QBP
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
FAM98A
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI1
MSI2
MYEF2
NOL6
NONO
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PURA
RBFOX2
RBM14
RBM4
RBM47
RBMS2
RTCB
SF3B1
SF3B3
SFPQ
SPOUT1
STRBP
SUGP2
SYNCRIP
TAF15
TRA2A
TRA2B
TRIM25
TRIM71
UPF1
UTP20
YBX1
YBX3
ZFR
ZNF346
89 interacting genes:
AIMP2
ARL4D
CDC42
DUS2
DUX4
EEF1D
ESR1
HSP90AA1
IARS1
LINC01554
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NEDD4
NELFCD
PTEN
RARS1
SUMO2
SYNCRIP
TAB1
Entrez ID
407024
2058
HPRD ID
00703
Ensembl ID
ENSG00000283797
ENSG00000136628
Uniprot IDs
P07814
PDB IDs
1FYJ
4HVC
4K86
4K87
4K88
5A1N
5A34
5A5H
5BMU
5V58
5VAD
5Y6L
6IY6
Enriched GO Terms of Interacting Partners
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